The 2003 Gordon Conference on Elastin and Elastic Tissue

2003 年戈登弹性蛋白和弹性组织会议

• 批准号: 6680447
• 负责人: STEVEN D SHAPIRO
• 金额: $ 1.5万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2003
• 资助国家: 美国
• 起止时间: 2003-09-19 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6680447
• 关键词: elastic tissue; elastin; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): This application requests funds to provide support for the twelfth bi-annual Gordon Research Conference on Elastin and Elastic Fibers to be held from August 3-8, 2003. The objective of this meeting is to provide a format for the exchange and integration of new information on the molecular and cell biology, biochemistry, biosynthesis, assembly, and pathobiology of elastin and micro fibrils. The proposed meeting will bring together basic scientists from a variety of disciplines to present and discuss the most recent information on elastin and microfibrillar proteins. This Conference will act as a major stimulus for international research into the nature and function of these unusual and important connective tissue proteins. Many novel findings related to elastic and microfibrillar proteins have been made since the 2001 Elastin and Elastic Fiber Gordon Conference. Among these include the role of elastic fibers in development and other biological processes, their utility in biomaterials and tissue engineering, and insights into their function and role in diseases such as COPD from functional genomics. In addition, much new biological functions of elastases have also been achieved largely through gene targeting. These functions include inflammatory functions as well as host defense against tumor progression and microbes. Thus, the 2003 Elastin and Elastic Fiber Gordon Conference will occur at an exciting time in connective tissue biology and will provide a mechanism to discuss these new findings. As in past years, these personal interactions will result in new collaborative studies and stimulate novel avenues of investigation of these important matrix proteins.

DESCRIPTION (provided by applicant): This application requests funds to provide support for the twelfth bi-annual Gordon Research Conference on Elastin and Elastic Fibers to be held from August 3-8, 2003. The objective of this meeting is to provide a format for the exchange and integration of new information on the molecular and cell biology, biochemistry, biosynthesis, assembly, and pathobiology of elastin and micro fibrils.拟议的会议将汇集来自各个学科的基本科学家，以介绍和讨论有关弹性蛋白和微纤维蛋白的最新信息。这次会议将成为对这些不寻常和重要的结缔组织蛋白质和功能的国际研究的主要刺激。自2001年弹性蛋白和弹性纤维Gordon会议以来，已经做出了许多与弹性和微纤维蛋白有关的新发现。其中包括弹性纤维在发育和其他生物过程中的作用，它们在生物材料和组织工程中的效用，以及对它们在功能基因组学等疾病（例如COPD）中的功能和作用的见解。此外，还主要通过基因靶向来实现弹性酶的许多新生物学功能。这些功能包括炎症功能以及宿主防御肿瘤进展和微生物。因此，2003年的弹性蛋白和弹性纤维戈登会议将在结缔组织生物学的激动人心的时刻举行，并将提供一种讨论这些新发现的机制。与过去几年一样，这些个人互动将导致新的合作研究，并刺激对这些重要基质蛋白的研究途径。