Diabetes and Cardiovascular Disease in Filipina Women

菲律宾女性的糖尿病和心血管疾病

• 批准号: 6620600
• 负责人: MARIA ROSARIO G. ARANETA
• 金额: $ 7.6万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6620600
• 关键词: Asian Americans; albuminuria; blood glucose; cardiovascular disorder; clinical research; comorbidity; diabetes mellitus therapy; diabetic angiopathy; diabetic nephropathy; diabetic ophthalmopathy; epidemiology; female; glycation; hemoglobin As; human middle age (35-64); human morbidity; human mortality; human old age (65+); human subject; insulin; insulin sensitivity /resistance; interview; noninsulin dependent diabetes mellitus; proinsulin; women's health

DESCRIPTION (provided by applicant): This proposal is designed to assess the relationship of noninsulin dependent diabetes (NIDDM) and its covariates to macrovascular and microvascular disease in a previously unstudied ethnic cohort by: 1. Providing support to an "under-represented investigator" Maria Rosario G. Araneta, Ph.D., an epidemiologist of Filipina descent. The present proposal will enable Dr. Araneta the opporunity to gain research experience in diabetes epidemiology, through the mentorship of Dr. Elizabeth Barrett-Connor, and collect and analyze data on which to base a subsequent research grant application on diabetes research. 2. Continuation of the UCSD Filipina Womens Health Study, a cross-sectional study of Filipina women aged 40 and above in San Diego County, through: a) a follow-up telephone interview to determine changes in morbidity, mortality, and medication use since their initial clinical evaluation in 1995-1999, and b) record review validation of reported cardiovascular disease. 3. Conducting statistical analyses of newly obtained data and data from the clinical evaluation to explore the relationship between NIDDM and its covariates, and the metabolic syndrome and its components to macrovascular (cardiovascular and lower extremity arterial disease) and microvascular disease (microalbuminuria, nephropathy, diabetes retinopathy, visual impairment and macular degeneration) among Filipina women.

描述（由申请人提供）： 该建议旨在评估非胰岛素依赖性的关系 糖尿病（NIDDM）及其对大血管和微血管疾病的协变量 在以前未研究的民族队列中： 1。为“代表性不足的调查员”玛丽亚·罗萨里奥·G（Maria Rosario G.）提供支持。 Araneta博士，菲律宾血统的流行病学家。目前的提议 将使Araneta博士获得抗糖尿病的研究经验 流行病学，通过伊丽莎白·巴雷特·科诺尔博士的指导， 收集和分析以后的研究赠款的数据 糖尿病研究的应用。 2. UCSD Filipina Womens Health研究的延续，横截面 圣地亚哥县40岁及以上的菲律宾妇女的研究：a）a） 后续电话采访以确定发病率，死亡率和 自1995年至1999年最初的临床评估以来，用药使用，b） 记录审查报告的心血管疾病的验证。 3。对新获得的数据和数据进行统计分析 临床评估以探索NIDDM与其之间的关系 协变量，代谢综合征及其对大血管的成分 （心血管和下肢动脉疾病）和微血管疾病 （微量白蛋白尿，肾病，糖尿病性病变，视觉障碍和 菲律宾妇女中的黄斑变性）。