Training in Synaptic Neurobiology

突触神经生物学培训

• 批准号: 6604211
• 负责人: JAMES R BAMBURG
• 金额: $ 25.73万
• 依托单位: COLORADO STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2007-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6604211
• 关键词: Training; Synaptic; Neurobiology

DESCRIPTION (provided by applicant) Integrated investigations using methods from biochemistry, molecular biology, cell biology, anatomy and physiology are central to advancing our understanding of synapse formation, organization and function. The purpose of the proposed program is to provide postdoctoral and predoctoral training focused in synaptic neurobiology. Our strategy for training gains from its ability to emphasize a specific set of current issues that require an interdisciplinary approach while still maintaining a breadth of training experience and exposure to a wide variety of intellectual tools. This research is the foundation for understanding - and hopefully alleviating - numerous neurological diseases. The training will be provided by 7 faculty members of the Molecular, Cellular and Integrative Neuroscience (MCIN) Program. The faculty members come from four departments in two colleges. These faculty, along with 14 others, have organized and teach a core neurobiology curriculum offering lecture, literature, laboratory and discussion courses. Within the program are individuals who can apply this fundamental knowledge in actual treatment of neurological disorders, through their joint appointments as clinical scientists at the Colorado State University Veterinary Teaching Hospital. In 2000 - 2001, 15 predoctoral and 20 postdoctoral students received training in the laboratories of the training faculty. These trainees were supported from individual research grants, postdoctoral and graduate fellowships, and by graduate assistantships from the MCIN Program. Most of the predoctoral trainees have degrees in traditional disciplines and were recruited either through participating departments or through the MCIN program. All of the postdoctoral trainees initiated contact with their mentors directly and were not recruited. The program described in this proposal would allow us to recruit 4 postdoctoral trainees and support 2 predoctoral students to participate in cross-disciplinary projects involving more than one laboratory for up to 3 years. These recruits will be important for strengthening the interactions between laboratories and will provide the trainees with a unique opportunity to acquire the multidisciplinary skills needed for success in today's research environment. All trainees will have access to modern cell and molecular biological facilities including computer enhanced light, confocal and electron microscopy (intermediate voltage), combined electrophysiology and light/fluorescence microscopy equipment, macromolecular synthesis and sequencing facilities, gene cloning and cell transfection laboratories, and a high quality lab animal resource facility.

描述（由申请人提供） 使用生物化学，分子生物学的方法进行的综合研究， 细胞生物学，解剖学和生理学对于促进我们的理解至关重要 突触形成，组织和功能。提议的目的 计划是提供集中于突触的博士后和尾训练培训 神经生物学。我们训练收益的策略，从其强调的能力中 需要跨学科方法的当前问题集 仍然保持广泛的培训经验和范围 各种智力工具。这项研究是 理解 - 希望减轻 - 许多神经系统疾病。这 培训将由分子，细胞和 综合神经科学（MCIN）计划。教师来自四个 两所大学的系。这些教师以及其他14位教师 组织和教授核心神经生物学课程，提供讲座， 文学，实验室和讨论课程。该程序中的是 可以将这种基本知识应用于实际治疗的个人 神经系统疾病，通过他们作为临床科学家的共同任命 在科罗拉多州立大学兽医教学医院。在2000年至2001年， 15个毒品前和20名博士后学生接受了培训 培训教师的实验室。这些学员得到了 个人研究赠款，博士后和研究生奖学金，以及 MCIN计划的研究生助学金。大多数现代学员 在传统学科中拥有学位，并通过 参与部门或通过MCIN计划。所有博士后 学员直接与导师联系，没有被招募。 本提案中描述的计划将使我们能够招募4个博士后 受训者和支持2名学生参加 跨学科项目涉及多个实验室，最多3个 年。这些新兵对于加强互动很重要 在实验室之间，将为受训者提供独特的机会 在当今的研究中获得成功所需的多学科技能 环境。所有学员都可以进入现代细胞和分子 生物设施，包括计算机增强的光，共聚焦和电子 显微镜（中间电压），电生理结合和 光/荧光显微镜设备，大分子合成和 测序设施，基因克隆和细胞转染实验室以及A 高质量的实验室动物资源设施。