PHOBIA, PANIC AND CONTROL OF BALANCE

恐惧症、恐慌和平衡控制

• 批准号: 6642904
• 负责人: ROLF G JACOB
• 金额: $ 34.88万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-08-01 至 2003-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6642904
• 关键词: anxiety disorders; auditory stimulus; balance; body movement; clinical research; human subject; neural information processing; panic disorder; phobias; proprioception /kinesthesia; sensory disorders; vestibuloocular reflex; visual stimulus

The overall objective of Subproject 6 is to investigate thepossible link between anxiety disorders and altered vestibular processing. This is based on the observation that panic attack and phobic avoidance are often prevalent in patients who present with balance disorders. Conversely, these investigators note that there seems to be a high prelevance of vestibular and balance dysfunction observed in patients who present with panic disorder and agoraphobia. These investigators aim to use a case control design in which they will examine vestibular correlates of the manifestations proposed in patients with anxiety disorders. Four groups of patients (n = 30) and a group of normal control subjects will be incorporated into the design of this study. Vestibular parameters to be assessed include the lateral semicircular canal-ocular reflex, using earth vertical axis rotation, and the otolith-ocular reflex, using off vertical axis rotation. Additionally, visual dependence for upright balance will be examined. Finally, the role of proprioception will be inferred by examining the effect of sway referencing to support surfaces. The data to be obtained in the experiments incorporated into the design are clearly articulated and there is a strong data analysis plan. The physical resources relevant to this project seem to be in place and there is every expectation that the goals of this project are likely to be met.

子项目6的总体目标是调查可能的联系 焦虑症和前庭处理改变之间的关系。这 基于这样的观察：惊恐发作和恐惧回避经常发生 常见于患有平衡障碍的患者。相反，这些 研究人员指出，前庭和 在患有惊恐障碍的患者中观察到平衡功能障碍 广场恐惧症。这些调查人员旨在使用病例对照设计，其中他们 将检查患者所提出的表现的前庭相关性 患有焦虑症。四组患者（n = 30）和一组正常人 对照受试者将被纳入本研究的设计中。前庭 要评估的参数包括外侧半规管眼反射， 使用地球垂直轴旋转和耳石眼反射，使用关闭 垂直轴旋转。此外，直立平衡的视觉依赖性 将接受检查。最后，本体感觉的作用将被推断为 检查参考支撑表面的摇摆效果。待数据 在纳入设计的实验中获得的结果得到了清晰的阐述 并且有强大的数据分析计划。相关物理资源 这个项目似乎已经到位，并且大家都期望能够实现目标 该项目的目标可能会得到满足。