The Influence of Drug Use on Suicide Ideation & Attempts

吸毒对自杀意念的影响

• 批准号: 6406347
• 负责人: Holly C Wilcox
• 金额: $ 3.7万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-20 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6406347
• 关键词: adolescence (12-20); aggression; alcoholism /alcohol abuse; behavioral /social science research tag; clinical research; cocaine; depression; drug abuse; human subject; longitudinal human study; marijuana abuse; nicotine; predoctoral investigator; suicide; young adult human (21-34)

DESCRIPTION: (Provided by Applicant) The specific aims of this predoctoral thesis research is to estimate the association between stages of drug use (i.e., nicotine, alcohol, marijuana and cocaine) and suicide ideation and attempts, within the context of a longitudinal study of young adults who originally were recruited and assessed as an epidemiological sample. The conceptual framework is oriented by the life-span developmental concepts of Kellam and Ensminger (1980), with elaboration of social context of the type espoused by Szapocznik and Coatsworth (1999). These specific aims will be studied with a prospective research design that involved repeated annual assessments of the 2,311 participating youths between their entry to first grade and age 14 years. They are now being followed up as young adults, with standardized assessments of drug disorders, suicide ideation and attempts, as well as possible mediators, e.g. depression and aggression. Statistical models used to estimate the associations will include GLM with a logistic link, survival analysis, latent trait models, and latent transition models. A power analysis is included as part of the proposal, as well as an overview of alternative procedures, weaknesses and counterbalancing strengths.

描述：（由申请人提供） 本博士前论文研究的具体目的是估计 吸毒阶段之间的关联（即尼古丁、酒精、大麻和 可卡因）和自杀意念和企图，在 对最初招募和评估的年轻人进行纵向研究 作为流行病学样本。概念框架的导向是 Kellam 和 Ensminger (1980) 的生命周期发展概念 对 Szapocznik 和 Coatsworth 所推崇的社会背景的阐述 （1999）。这些具体目标将通过前瞻性研究设计进行研究 其中涉及对 2,311 名参与青年进行反复年度评估 从他们进入一年级到 14 岁。他们现在正被 对年轻人进行随访，对药物失调进行标准化评估， 自杀意念和企图，以及可能的调解因素，例如沮丧 和侵略性。用于估计关联性的统计模型 包括具有逻辑联系的 GLM、生存分析、潜在特征模型，以及 潜在的转变模型。提案中包含功率分析， 以及替代程序、弱点和的概述 平衡优势。