SCHOOL AGE OUTCOMES OF <1000 GRAM BIRTHWEIGHT CHILDREN

出生体重 <1000 克儿童的学龄结果

• 批准号: 6637984
• 负责人: MAUREEN HACK
• 金额: $ 40.57万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-15 至 2005-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6637984
• 关键词: academic achievement; behavioral /social science research tag; child behavior; child physical development; child psychology; clinical research; cognition; developmental neurobiology; epidemiology; family structure /dynamics; functional ability; human subject; interview; longitudinal human study; low birth weight infant human; middle childhood (6-11); neuropsychological tests; outcomes research; pediatrics; psychometrics; questionnaires; socioeconomics

This proposal requests support for a comprehensive examination of the multiple functional outcomes and special health care needs of <1000 gm birth weight children at school age. A cohort of 221 <1000 gm children born 1992-1995 was evaluated at 20 months corrected age at which time 48% had neurologic and/or developmental impairment. In the proposed study, we plan to examine their school age functioning and special health care needs at age 8 years compared to normal birth weight school controls matched by age, gender and race. To assess Health Status and Special Health Care Needs, we plan to use recently developed measures of child health (the Child Health and Illness Profile (CHIP-CE) and the Questionnaire for Identifying Children with Chronic Diseases (QuICCC), together with the more traditional categorical measures of neurosensory and developmental outcome. Data collection will include parent, child and teacher questionnaires and interviews, direct assessment of physical and neurosensory status and psychometric testing We hypothesize that the outcomes of the < 1000 gm birth weight children will differ in three ways from outcomes of the normal birth weight controls at age 8 years; a) From the parent and child's perspective, children of <1000 gm birth weight will have poorer general health status and more functional limitations, need for compensatory aids and services above routine; b) Using direct assessment methods and teacher report, < 1000 gm birth weight children will have higher rates of subnormal growth, neurosensory impairments and poorer cognitive ability, academic achievement, neuropsychologic functioning and school performance; and c) Parents of < 1000 gm birth weight children will report a negative impact on the family including higher rates of family dysfunction, maternal depression and economic hardship. Data analysis will include examination of group differences; the relationship of direct assessments of the child to parent and child-based reports of health outcomes; and the relationship of social and biologic factors to the child's functioning and to impact on the family. This study will provide critical research-based and policy related information needed both for measuring outcomes of neonatal intensive care and for the planning and provision of services for high risk children.

该提案要求支持对学龄<1000克出生体重儿童的多种功能结果和特殊医疗保健需求进行全面检查。对 1992 年至 1995 年出生的 221 名 <1000 克儿童进行了评估，其中 48% 的儿童患有神经系统和/或发育障碍，校正年龄为 20 个月。在拟议的研究中，我们计划检查他们 8 岁时的学龄功能和特殊医疗保健需求，并将其与年龄、性别和种族相匹配的正常出生体重学校对照组进行比较。为了评估健康状况和特殊医疗保健需求，我们计划使用最近开发的儿童健康衡量标准（儿童健康和疾病概况（CHIP-CE）和慢性病儿童识别问卷（QuICCC），以及更传统的方法）神经感觉和发育结果的分类测量将包括家长、儿童和教师的问卷调查和访谈、身体和神经感觉状态的直接评估以及心理测试。我们假设 < 1000 的结果。出生体重小于 1000 克的儿童与 8 岁时正常出生体重控制的结果在三个方面有所不同；超出常规的补偿性援助和服务； b) 使用直接评估方法和教师报告，出生体重<1000克的儿童生长发育不正常、神经感觉障碍的比例较高，认知能力、学业成绩、神经心理功能和学校表现较差； c) 出生体重 < 1000 克的儿童的父母将会报告对家庭的负面影响，包括家庭功能障碍、产妇抑郁和经济困难的发生率较高。数据分析将包括检查群体差异；儿童的直接评估与父母和儿童的健康结果报告之间的关系；以及社会和生物因素与儿童功能和对家庭影响的关系。这项研究将为衡量新生儿重症监护的结果以及为高危儿童规划和提供服务提供所需的关键研究和政策相关信息。