GENETICS OF BONE DENSITY IN MEXICAN AMERICANS

墨西哥裔美国人骨密度的遗传学

• 批准号: 6586840
• 负责人: RICHARD L BAUER
• 金额: $ 23.48万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-12-01 至 2002-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6586840
• 关键词: Mexican Americans; biomarker; bone density; clinical research; family genetics; human subject; photon absorptiometry

Using the same study cohort as the Genetics of Atherosclerosis in Mexican Americans study, this protocol has as its objective the identification and characterization of the genetic determinants of low bone density. Since the cohort has already had extensive interviews on a wide range of lifestyle and medical variables, there is a base from which to perform further study. The individuals will be re-examined and bone density will be measured at three sites by dual photon absorptiometry (DEXA). Additional biochemical markers of bone density-related phenotypes will also be obtained.

该方案使用与墨西哥美国人动脉粥样硬化遗传学研究相同的研究队列，其目标是识别和表征低骨密度的遗传决定因素。 由于该队列已经对广泛的生活方式和医疗变量进行了广泛的采访，因此有一个进行进一步研究的基础。 这些个体将接受重新检查，并通过双光子吸收法 (DEXA) 在三个部位测量骨密度。 还将获得骨密度相关表型的其他生化标志物。