U Guam RISE equipment supplement for R25 GM63682-01

U 关岛 RISE R25 GM63682-01 设备补充

• 批准号: 6569432
• 负责人: CHRISTOPHER SIMON LOBBAN
• 金额: $ 14.5万
• 依托单位: UNIVERSITY OF GUAM
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-08-01 至 2004-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6569432
• 关键词: Pacific Islander; computer center; health science research potential; interdisciplinary collaboration; minority health professional; minority institution research support; predoctoral investigator; science education; travel; university student

DESCRIPTION (provided by applicant): The three instruments requested here will significantly enhance the biomedical research climate for students and faculty at the University of Guam. This will immediately serve the RISE goals of student and faculty development, and will add to integration of teaching and research that will motivate more students to complete the baccalaureate degree and go on to graduate school, and more teaching faculty to publish and apply for research grants. The three instruments requested include a low-field nuclear magnetic resonance (NMR) spectrometer, a VersaDoc 1000 Imager, and a differential interference contrast (DIC)/fluorescence microscope to support training of students in modern microscopy. Each of these instruments will serve all our biology and chemistry majors (-60-70 students) through 9 chemistry and 8 biology courses. By using the instruments in different courses, students will develop the ability to apply the techniques to novel situations in their research. The equipment will also be used in faculty research projects, often with students, which will increase output of presentations and publications and contribute preliminary data toward grant applications. The Data from the Imager and microscope will be shared through the new RISE Science LAN. Provision has been made for maintenance of the equipment by the University under the responsibility of the named faculty. NMR is one of the most important and powerful spectroscopic techniques in organic and biochemistry, but is not currently available on Guam. The NMR most suited to our teaching needs, small institution size, and remote location is a refurbished 60 MHz Fourier Transform spectrometer equipped with a permanent magnet and 1H and _C Probes. This system is much more resilient than a superconducting 300 MHz instrument, requires no cryogenics, and can and maintained by the University with available resources. The chemist in charge attended an NSF-sponsored workshop on NMR last year The VersaDoc Imager and associated statistical analyses will allow us to advance the genetics and molecular labs into quantitative analysis. Students will learn to design experiments with precision to accurately estimate population genetic parameters and will be able to implement the types of automated, quantitative measurements they will need in biomedical research. With the DIC/FL microscope students will learn to select and set up appropriate optics for biodiversity and cytology studies. The superior views of living biological specimens from DIC optics in the microscope will deepen students' understanding of biological systems and further their contribution to research into the marine biota of Guam.

描述（由申请人提供）：此处要求的三件仪器将显着改善关岛大学学生和教师的生物医学研究氛围。这将立即服务于学生和教师发展的 RISE 目标，并将促进教学和研究的整合，从而激励更多的学生完成学士学位并继续进入研究生院，以及更多的教师发表和申请研究经费。所需的三台仪器包括低场核磁共振 (NMR) 波谱仪、VersaDoc 1000 成像仪和微分干涉衬度 (DIC)/荧光显微镜，以支持学生进行现代显微镜培训。这些仪器中的每一个都将通过 9 门化学和 8 门生物学课程为我们所有生物和化学专业（-60-70 名学生）提供服务。通过在不同课程中使用这些工具，学生将培养将这些技术应用于研究中新情况的能力。该设备还将用于教师研究项目（通常是与学生一起），这将增加演示和出版物的产出，并为拨款申请提供初步数据。来自成像仪和显微镜的数据将通过新的 RISE Science LAN 共享。大学已规定由指定教师负责维护设备。核磁共振是有机和生物化学领域最重要、最强大的光谱技术之一，但目前在关岛尚不可用。最适合我们的教学需求、小型机构规模和远程位置的 NMR 是配备永磁体以及 1H 和 _C 探头的翻新 60 MHz 傅立叶变换光谱仪。该系统比超导 300 MHz 仪器更具弹性，不需要低温，并且可以由大学利用可用资源进行维护。负责的化学家去年参加了 NSF 赞助的 NMR 研讨会。VersaDoc 成像仪和相关的统计分析将使我们能够将遗传学和分子实验室推进到定量分析。学生将学习精确设计实验，以准确估计群体遗传参数，并将能够实施生物医学研究中所需的自动化定量测量类型。通过 DIC/FL 显微镜，学生将学习选择和设置适合生物多样性和细胞学研究的光学器件。显微镜中 DIC 光学器件对活体生物标本的卓越观察将加深学生对生物系统的理解，并进一步为关岛海洋生物群的研究做出贡献。