ADVANCED TECHNOLOGY QA CENTER

先进技术质量保证中心

• 批准号: 6377235
• 负责人: JAMES A PURDY
• 金额: $ 82.51万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-22 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6377235
• 关键词: cancer information system; cancer registry /resource; cooperative study; data collection methodology /evaluation; data management; human therapy evaluation; neoplasm /cancer radiation therapy; outcomes research; patient care management; patient care planning; radiography; technology /technique development

It is well recognized that there are several programs within the United States that are capable of developing Quality Assurance programs for advanced technologies in radiation therapy. The goal of this application is to capitalize on the infrastructure and strengths of several Quality Assurance programs to develop a superstructure capable of developing Quality Assurance programs for advanced radiation technologies. The goal of this endeavor is to utilize the strengths of these defined programs in developing uniformity in quality assurance in advanced technologies throughout all participating Cooperative Groups. Specifically we propose to (1) develop quality assurance programs in three-dimensional conformal therapy that will be uniform to all Cooperative Groups who choose to participate in this program; (2) develop equivalent programs in brachytherapy to multiple body part sites to ensure uniformity and quality assurance and establish standards in normal tissue tolerance; (3) establish uniform guidelines in database interpretation that allow for all dose-volume histogram analysis for tumor volume and normal tissue to be housed in one database. We will also establish a program to house data in both tumor volume coverage and normal tissue coverage to enhance our knowledge about outcome analysis; (4) To provide appropriate storage and interpretation of diagnostic x-rays required for protocol analysis; (5) develop QA programs for further advanced technology treatment programs such as Intensity Modulated Radiation Therapy.

众所周知，美国境内有几个计划能够为放射疗法的高级技术开发质量保证计划。 该应用程序的目的是利用几种质量保证计划的基础设施和优势，以开发能够为高级辐射技术开发质量保证计划的上层建筑。 这项努力的目的是利用这些定义计划的优势来发展所有参与合作团体的高级技术质量保证的统一性。具体而言，我们建议（1）在三维形式的共形疗法中制定质量保证计划，这对于所有选择参加该计划的合作团体都将是统一的； （2）将近距离放射治疗的等效程序与多个身体部位部位开发，以确保均匀性和质量保证并在正常组织耐受性中建立标准； （3）在数据库解释中建立统一的准则，以便将所有剂量 - 体积直方图分析用于肿瘤体积和正常组织中，并将其容纳在一个数据库中。 我们还将建立一个计划，以容纳肿瘤体积覆盖范围和正常组织覆盖范围的数据，以增强我们对结果分析的了解； （4）提供协议分析所需的诊断X射线的适当存储和解释； （5）为进一步的先进技术治疗计划（例如强度调制放射疗法）制定质量检查计划。