Nasal Contour Pack for Epistaxis

鼻出血鼻轮廓包

• 批准号: 6484009
• 负责人: PAUL P BUREK
• 金额: $ 9.95万
• 依托单位: ROSE BIOMEDICAL DEVELOPMENT CORPORATION
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-05-20 至 2002-11-19
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6484009
• 关键词: bioengineering /biomedical engineering; biomaterial compatibility; biomedical equipment development; blood coagulation; clinical research; emergency health services; hemorrhage; hemostasis; hospital equipment /supply; human tissue; mechanical pressure; polyvinyls; portable biomedical equipment; respiratory oxygen

Epitaxis, otherwise known as nosebleed, is a common occurrence that typically responds to home treatment. Some cases, however, do not respond and a significant number of patients require emergency room treatment. In severe cases, hospital admittance and time in intensive care are necessary. Several methods of treatment have evolved for treatment of epistaxis: 1) gauze packing, 2) balloon and 3) desiccated sponge packs. Each strategy has strengths, but also weaknesses. Gauze packing decreases blood oxygen levels and is extremely painful, requiring administration of narcotics. Nasal balloons resist conformation to the intricacies of the nasal cavity. Desiccated sponges are solid and immalleable during insertion, often damaging the nasal mucosa. RBDC proposes to develop and test the Nasal Contour Pack (C-Pack). The C-Pack has a soft PVC tube base for easy insertion and removal with two thin, soft plastic bags mounted on top of the tube. Once inserted, the bags can be inflated to create sufficient pressure to stop the bleed. The soft bags will work into the various crevices, create even pressure, will insert easily, can be deflated for easy removal. It will be much less painful, will not require narcotics, and have a channel to provide supplemental oxygen. PROPOSED COMMERCIAL APPLICATIONS: Epistaxis remains one of the most common acute ENT disorders resulting in hospital admissions. Approximately 5-10% of the population experience an episode of active nasal bleed each year. Approximately 10% of these patients visit a physician and one in 10 will require hospitalization. A device that imposes none of the disadvantages of current technology, that can be inserted in an exact and simple manner, is effective as initial intervention and that could be produced at no greater expense than existing devices, would find a prominent place within the market.

外伤，也称为鼻出血，是一种常见现象，通常可以通过家庭治疗得到缓解。然而，有些病例没有反应，大量患者需要急诊室治疗。在严重的情况下，需要入院并接受重症监护。鼻出血的治疗方法已经发展出几种：1）纱布填塞，2）球囊和3）干燥海绵填塞。每种策略都有优点，但也有缺点。纱布填塞会降低血氧水平，并且非常痛苦，需要服用麻醉剂。鼻球囊可抵抗鼻腔的复杂结构。干燥的海绵在插入过程中是固体且不可延展的，通常会损坏鼻粘膜。 RBDC 提议开发和测试 Nasal Contour Pack (C-Pack)。 C-Pack 具有柔软的 PVC 管底座，可轻松插入和取出，管顶部安装有两个薄的柔软塑料袋。一旦插入，袋子可以充气以产生足够的压力来止血。柔软的袋子可以进入各种缝隙，产生均匀的压力，可以轻松插入，可以放气以便于取出。它会减轻很多痛苦，不需要麻醉剂，并且有一个提供补充氧气的通道。拟议的商业应用：鼻出血仍然是导致入院的最常见的急性耳鼻喉疾病之一。每年大约 5-10% 的人口会经历一次活动性鼻出血。这些患者中大约 10% 会去看医生，十分之一需要住院治疗。一种设备不会带来现有技术的任何缺点，能够以精确和简单的方式插入，作为初始干预是有效的，并且其生产成本不高于现有设备，将在市场上占据显着地位。