THE GENETIC BASIS OF VARIATION IN OLFACTORY BEHAVIOR

嗅觉行为变异的遗传基础

• 批准号: 6489936
• 负责人: Stephanie Marie Rollmann
• 金额: $ 4.42万
• 依托单位: NORTH CAROLINA STATE UNIVERSITY RALEIGH
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-21 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/6489936
• 关键词: Drosophilidae; RNase protection assay; alleles; animal communication behavior; animal population study; arthropod genetics; behavior test; behavioral /social science research tag; behavioral genetics; chemoreceptors; gene complementation; gene expression; genetic polymorphism; genotype; in situ hybridization; northern blottings; olfactions; polymerase chain reaction; regulatory gene; single nucleotide polymorphism; single strand conformation polymorphism; southern blotting; transposon /insertion element

Many organisms obtain critical information from the environment through olfactory signals. For instance, chemical signals are used for food localization, species identification, and mate recognition. Thus, the ability to perceive and respond to these signals is essential for an organism's survival and reproduction. The ultimate goal of the proposed research is to understand the genetic basis for variation in behavior in natural populations as it relates to chemical communication. The specific aims of this project are: (1) To characterize smell impaired (smi) loci in co-isotonic lines of D, melanogaster, and (2) To investigate how molecular variation in these loci contributes to variation in odor-guide behavior in a natural population. These studies will provide for the first time information about the effect of single nucleotide polymorphism's in defined genes on odor-guide behavior in natural population.

许多生物体通过嗅觉信号从环境中获取关键信息。例如，化学信号用于食物定位、物种识别和配偶识别。因此，感知和响应这些信号的能力对于生物体的生存和繁殖至关重要。拟议研究的最终目标是了解自然群体行为变异的遗传基础，因为它与化学通讯有关。该项目的具体目标是：(1) 表征黑腹果蝇共等渗品系中的嗅觉受损 (smi) 位点，以及 (2) 研究这些基因座中的分子变异如何影响黑腹果蝇气味引导行为的变化。自然人口。这些研究将首次提供有关特定基因中的单核苷酸多态性对自然群体气味引导行为的影响的信息。