CORE--DEVELOPMENTAL

核心--发展

• 批准号: 6485952
• 负责人: JONATHAN P LEIS
• 金额: $ 19.62万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6485952
• 关键词: AIDS; biomedical facility; health science research support; AIDS; biomedical facility; health science research support

The purpose of the CFAR Developmental Core is to stimulate the growth of AIDS-related research at Case Western Reserve University and its affiliates by fostering translational basic/clinical research developing experimental technologies whose application will advance AIDS-related research, promoting interactions with other Centers on the Case Western Reserve University campus. A Developmental Core administrative structure has been established to distribute and monitor the use of developmental funds through a variety of mechanisms including (1) investigator initiated feasibility studies, (2) request for specific applications, (3) new technology development, (4) faculty recruitment, (5) state-of-the-art core development, (6) CFAR supplement applications, and (7) inter-center coordination. As a result of Developmental Core activities over a three year period, 12 new members have joined the CFAR, 5 manuscripts have been published, 5 national research grants totaling $2.9 million in direct costs, (including 1 minority supplement grant) have been funded, two new faculty members with a focus on AIDS-related research have been recruited to Case Western Reserve University, an ELIspot technology has been patented by Case Western Reserve University and provided as a service by a new CFAR Cytokine Core, thre other CFAR Cores have been enhanced, and several inter-center program initiatives have been developed. Developmental Core funds of $150,000/year are requested for years 06-10 to be used to support the Developmental Core programs as outlined above. In year 06, $75,000 will be used for faculty recruitment and the remained used to support investigator initiated feasibility studies and core development. In year 06 and in subsequent years, developmental Core funds will be distributed at the discretion of the CFAR leadership on a basis where the funds may have the greatest impact in stimulating AIDS-related research activities.

CFAR发展核心的目的是刺激 Case Western Reserve University及其与AIDS有关的研究 通过促进转化基本/临床研究的构图 实验技术的应用将推动与艾滋病有关 研究，促进与西方案件的其他中心的互动 预备大学校园。发展性核心行政结构 已建立以分发和监视发展的使用 通过包括（1）调查员启动的各种机制的资金 可行性研究，（2）请求特定申请，（3）新的 技术发展，（4）教师招聘，（5）最先进的核心 开发，（6）CFAR补充应用和（7）中心间 协调。 由于发展核心活动在三年内，有12个 新成员加入了CFAR，已出版了5份手稿，5个手稿 国家研究授予总计290万美元的直接费用（包括 1个少数民族补助金）已被资助，两名新教师 以与艾滋病相关的研究重点是西方案件 储备大学，ELISPOT技术已获得案例专利 西部储备大学，并由新的CFAR作为服务 细胞因子核心，其他CFAR核心已增强，有几个 中心计划计划已经开发出来。 要求以每年15万美元的核心资金为06 - 10年 如上所述，可用于支持发展核心计划。在 06年，$ 75,000将用于招聘教职员工，剩下的 用于支持研究者的启动可行性研究和核心 发展。在第06年以及随后的几年中，发展核心基金 将由CFAR领导层酌情分发 资金可能在刺激艾滋病有关的情况下产生最大的影响 研究活动。