EXPERIENCE AND NEUROCHEMISTRY OF THE SYNAPSE

突触的体验和神经化学

• 批准号: 6539554
• 负责人: RICHARD E ZIGMOND
• 金额: $ 35.26万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-05-01 至 2004-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6539554
• 关键词: axon reaction; denervation; gene induction /repression; laboratory rat; messenger RNA; neural plasticity; neural transmission; neurochemistry; neuropeptide Y; neuroregulation; neurotransmitter biosynthesis; neurotrophic factors; nicotinic receptors; organ culture; protein isoforms; receptor expression; second messengers; superior cervical ganglion; synapses; vasoactive intestinal peptide

项目成果

Galanin expression is decreased by cAMP-elevating agents in cultured sympathetic ganglia.

在培养的交感神经节中，cAMP 升高剂可降低甘丙肽的表达。

• DOI: 10.1097/00001756-199904260-00012
• 发表时间: 1999
• 期刊: Neuroreport
• 影响因子: 1.7
• 作者: Mohney,RP;Zigmond,RE
• 通讯作者: Zigmond,RE

Substance P inhibits the acute stimulation of ganglionic tyrosine hydroxylase activity by a nicotinic agonist.

P 物质抑制烟碱激动剂对神经节酪氨酸羟化酶活性的急性刺激。

• DOI: 10.1016/0306-4522(84)90271-9
• 发表时间: 1984
• 期刊: Neuroscience
• 影响因子: 3.3
• 作者: Ip,NY;Zigmond,RE
• 通讯作者: Zigmond,RE

Localization of neurons in the rat spinal cord which project to the superior cervical ganglion.

大鼠脊髓中投射到颈上神经节的神经元的定位。

• DOI: 10.1002/cne.901960107
• 发表时间: 1981
• 期刊: The Journal of comparative neurology
• 作者: Rando,TA;Bowers,CW;Zigmond,RE
• 通讯作者: Zigmond,RE

Both nicotinic and muscarinic agonists acutely increase tyrosine 3-monooxygenase activity in the superior cervical ganglion.

烟碱和毒蕈碱激动剂均可急剧增加颈上神经节中酪氨酸3-单加氧酶的活性。

• 发表时间: 1982
• 期刊: The Journal of pharmacology and experimental therapeutics
• 作者: Ip,NY;Perlman,RL;Zigmond,RE
• 通讯作者: Zigmond,RE

Activation of ganglionic tyrosine hydroxylase by peptides of the secretin-glucagon family: structure-function studies.

促胰液素-胰高血糖素家族肽激活神经节酪氨酸羟化酶：结构功能研究。

• DOI: 10.1016/0306-4522(89)90037-7
• 发表时间: 1989
• 期刊: Neuroscience
• 影响因子: 3.3
• 作者: Schwarzschild,MA;Vale,W;Corigliano-Murphy,AC;Pisano,JJ;Ip,NY;Zigmond,RE
• 通讯作者: Zigmond,RE