Gordon Research Conference:Cardiac Regulatory Mechanisms

戈登研究会议：心脏调节机制

• 批准号: 6513762
• 负责人: R John Solaro
• 金额: $ 1万
• 依托单位: UNIVERSITY OF ILLINOIS AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-07-01 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6513762
• 关键词: heart failure; meeting /conference /symposium; travel

DESCRIPTION (provided by applicant): This application seeks partial funding for the Gordon Research Conference on Cardiac Regulatory Mechanisms, which will be held July 28, 2002 to August 2, 2002 at Connecticut College in New London, CT. The Gordon Research Conference on Cardiac Regulatory Mechanisms has had a highly successful history of success. The most important goal of this meeting is to bring together the most talented and productive scientists from different disciplines concerned with far ranging aspects of cardiac regulation. A specific objective is to create an atmosphere of inclusive, intense, and live discussions where all contribute. The informal nature of the GRC has through the years been a fertile matrix for the generation of new ideas and new personal and scientific connections. It is a great venue for inclusion of young investigators. These interactions are vital to our understanding of the relation between basic molecular and cellular mechanisms and the overt manifestation of cardiac regulation in health and disease. The unifying theme of the GRC meeting in 2002 is heart failure. This is an exciting time in cardiac research with the best scientists turning their attention to translation of the basic molecular and cellular biology of heart cells to diagnosis, prevention, and treatment of heart failure. In a meeting such as this it is truly possible to have realistic discussions of topics from molecules to man framed in workshops and symposia with heart failure as an underlying theme. The times are also exciting because many of the molecules regulating cardiac function have been identified, their genes have been cloned and genetic linkage to the syndrome of hypertrophy and failure of the heart is unfolding. The emergence of new technologies related to genomic and proteomics have the promise of making the connection between structure and function more firm. How hypertrophy and failure of the heart may arise from alterations in structure/function relations will be emphasized in the 2002 GRC conference. The conference not only includes cutting edge science but also the impact of emerging technologies on our ability to probe molecular mechanisms. These emerging technologies are the subjects of sessions on genomics and DNA arrays, informatics, and proteomics. The meeting will also include meaningful "phenotyping" as an explicit topic. Other sessions that are novel and timely deal with Gender Related Differences, Integrative Biology and Mathematic Modeling, Metabolic Adaptation and Gene Expression, and Localization and Scaffolding in Cell Signaling. Much of the time of the meeting is devoted to debates and discussion. Presentations of late breaking science from young investigator will be added from the posters submitted to the meeting.

说明（由申请人提供）：本申请为戈登心脏调节机制研究会议寻求部分资助，该会议将于 2002 年 7 月 28 日至 8 月 2 日在康涅狄格州新伦敦的康涅狄格学院举行。 戈登心脏调节机制研究会议有着非常成功的历史。 这次会议最重要的目标是汇集来自不同学科、关注心脏调节广泛方面的最有才华和生产力的科学家。 具体目标是营造一种包容、激烈、生动的讨论氛围，让所有人都做出贡献。 多年来，GRC 的非正式性质一直是产生新想法以及新的个人和科学联系的沃土。 这是吸引年轻研究者的绝佳场所。 这些相互作用对于我们理解基本分子和细胞机制以及健康和疾病中心脏调节的明显表现之间的关系至关重要。 2002 年 GRC 会议的统一主题是心力衰竭。 这是心脏研究的一个激动人心的时刻，最优秀的科学家将注意力转向将心脏细胞的基本分子和细胞生物学转化为心力衰竭的诊断、预防和治疗。 在这样的会议中，确实可以在以心力衰竭为基本主题的研讨会和研讨会上对从分子到人的主题进行现实的讨论。 这个时代也令人兴奋，因为许多调节心脏功能的分子已经被识别，它们的基因已经被克隆，并且与心脏肥大和衰竭综合征的遗传联系正在显现。 与基因组学和蛋白质组学相关的新技术的出现有望使结构和功能之间的联系更加牢固。 2002 年 GRC 会议将强调结构/功能关系的改变如何引起心脏肥大和衰竭。 会议不仅包括尖端科学，还包括新兴技术对我们探索分子机制的能力的影响。 这些新兴技术是基因组学和 DNA 阵列、信息学和蛋白质组学会议的主题。 会议还将有意义的“表型分析”作为一个明确的主题。 其他新颖且及时的会议涉及性别相关差异、综合生物学和数学建模、代谢适应和基因表达以及细胞信号传导中的定位和支架。 会议的大部分时间都用于辩论和讨论。 年轻研究者最新突破性科学的展示将从提交给会议的海报中添加。