ATHEROSCLEROSIS RISK FACTORS IN MINORITY SLE PATIENTS

少数 SLE 患者的动脉粥样硬化危险因素

• 批准号: 6414495
• 负责人: Peter E Lipsky
• 金额: $ 32.14万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-12-01 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6414495
• 关键词: atherosclerosis; blood chemistry; cholesterol; clinical research; diet therapy; dietary lipid; disease /disorder proneness /risk; ethnic group; female; human subject; human therapy evaluation; inflammation; low density lipoprotein; nutrition related tag; systemic lupus erythematosus

The main aim of the study is to determine the effectiveness of a cholesterol lowering diet on low-density lipoprotein cholesterol (LDL) in minority females patients with systemic lupus erythematosus (SLE). It is hypothesized that patients on a cholesterol reducing diet will reduce their LDL significantly compared to patients in the control group. The secondary purpose of the study is to investigate whether inflammation decreases with a decrease in LDL level or SLE activity.

该研究的主要目的是确定 低密度脂蛋白胆固醇（LDL）的胆固醇降低饮食 在少数族裔女性中，患有红斑狼疮的患者（SLE）。 假设降低胆固醇饮食的患者将 与对照中的患者相比 团体。 该研究的次要目的是调查是否 炎症随着LDL水平或SLE活性的降低而减少。