MODEL FOR CATALYTIC REDUCTIVE DEHALOGENATION

催化还原脱卤模型

• 批准号: 6106237
• 负责人: ROBERT Glenn ARNOLD
• 金额: $ 12.65万
• 依托单位: UNIVERSITY OF ARIZONA
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-04-01 至 2000-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6106237
• 关键词: anaerobiosis; bioreactors; biotransformation; carbon tetrachloride; catalyst; cell free system; cellular respiration; chlorohydrocarbon; detoxification; electrical potential; electrochemistry; electrodes; electron transport; environmental contamination; environmental engineering; environmental toxicology; halogenation; microorganism metabolism; organometallic compounds; photolysis; reducing agents; reduction; semiconduction; vitamin B12; waste treatment

This project is engineering oriented and investigates treatment technologies for heavily halogenated organic pollutants. These pollutants have generally proven to be resistant to aerobic biochemical treatment measures. Numerous investigators have recognized the potential advantages of reductive dehalogenation as a mechanism for pretreating such compounds for subsequent aerobic transformations. Staged treatments of this nature would eliminate potential hazards from the release of partially dehalogenated products of reductive processes. Both abiotic and biochemically driven reductive dehalogenation of chlorinated solvents are proposed for study and evaluation in this project. The abiotic and biochemical foci will be studied and developed via three model systems that promote dehalogenation of haloorganic compounds that would be applicable for use under field conditions. Proposed work includes: 1) fundamental and applied investigations into the use of semiconductor-macrocycle hybrid catalysts for the reductive dehalogenation of aqueous-phase halogenated organics; 2) parallel development of in situ groundwater treatment systems based on the use of zero-valence metals (Fe and zn) for the reductive dehalogenation of reductive targets; and 3) isolation and identification of the physiological elements responsible for the reductive dehalogenation of carbon tetrachloride by Shewanella putrefaciens 200.

本项目以工程为导向，研究处理 重卤有机污染物治理技术。 这些 污染物通常被证明对有氧生化具有抵抗力 治疗措施。 许多研究人员已经认识到这种潜力 还原脱卤作为预处理机制的优点 此类化合物用于随后的需氧转化。 分阶段治疗 这种性质将消除释放的潜在危险 还原过程的部分脱卤产物。 两者都是非生物的 和生化驱动的氯化溶剂的还原脱卤 建议在本项目中进行研究和评估。 非生物和生化焦点将通过三个方面进行研究和开发 促进卤代有机化合物脱卤的模型系统 适合在现场条件下使用。 拟议的工作 包括：1）对使用的基础和应用研究 用于还原反应的半导体-大环杂化催化剂 水相卤代有机物的脱卤； 2）并联 开发基于使用的原位地下水处理系统 零价金属（Fe 和 Zn）用于还原脱卤 减少目标； 3) 隔离和鉴定 负责还原脱卤的生理元素 由腐败希瓦氏菌 200 产生的四氯化碳。