TRENDS IN TRANS-FATTY ACID INTAKE BETWEEN 1980 AND 1997

1980 年至 1997 年反式脂肪酸摄入量趋势

• 批准号: 6390678
• 负责人: LISA HARNACK
• 金额: $ 7.11万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-04-01 至 2002-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6390678
• 关键词: cardiovascular disorder epidemiology; clinical research; dietary lipid; disease /disorder proneness /risk; health surveys; human data; nutrition related tag; unsaturated fatty acids

DESCRIPTION (Adapted from the applicant's abstract) In recent years concern has arisen about the potential health hazards of trans-fatty acids in the American diet. Dietary intake of trans-fatty acids has been linked to unhealthy shifts in serum lipid profiles and to coronary heart disease (CHD) in a number of studies. Although several studies have estimated intakes of trans-fatty acids in U.S. populations, presently data is lacking regarding trends in intake of trans-fatty acids in the population. Furthermore, it is unclear how trends in intake of trans-fatty acids may be related to changes in other dietary and non-dietary CHD risk factors and CHD mortality. This proposal aims to utilize newly available nutrient data to recalculate dietary data collected as part of the Minnesota Heart Survey (MHS) to examine trends in intake of trans-fatty acids. The MHS is an ongoing observational epidemiologic study of trends in risk factors and cardiovascular morbidity and mortality among independent cross-sectional probability samples of the Minneapolis-St. Paul, Minnesota, metropolitan area. Surveys were conducted in 1980-1982, 1985-1987, 1990-1992 and 1995-1997. Diet was among the CVD risk factors measured as part of each survey. In this research, 24-hour dietary recalls collected from MHS participants will be recalculated using an updated food and nutrient database that includes trans-fatty acid values (16:1, 18:1, 18:2, and total). Intake estimates resulting from recalculation will be analyzed to examine temporal trends in trans-fatty acid intake between 1980 and 1997, and to examine the relationship of temporal trends in trans-fatty acid intake to temporal changes in other dietary and non-dietary CHD risk factors and changes in CHD mortality. The MHS data provide a unique opportunity to examine a dietary constituent only recently recognized as a potential risk factor for CHD.

描述 （根据申请人的摘要改编）近年来引起了人们的关注 关于美国饮食中反式脂肪酸的潜在健康危害。 反式脂肪酸的饮食摄入与不健康的转变有关 血清脂质谱和冠状动脉疾病（CHD） 研究。 尽管几项研究估计了反式脂肪酸的摄入量 在美国人口中，目前缺乏有关摄入趋势的数据 人群中的跨脂肪酸。 此外，目前尚不清楚如何趋势 反式脂肪酸的摄入可能与其他饮食中的变化有关 非疾病危险因素和CHD死亡率。 该建议旨在利用新的营养数据来重新计算 作为明尼苏达州心脏调查（MHS）的一部分收集的饮食数据以检查 反式脂肪酸摄入的趋势。 MHS是一个持续的观察 流行病学研究危险因素和心血管发病率的趋势和 独立的横截面概率样本之间的死亡率 明尼阿波利斯圣。保罗，明尼苏达州，大都会地区。 进行调查 1980-1982，1985-1987，1990-1992和1995-1997。 饮食是CVD风险之一 每次调查的一部分测量的因素。 在这项研究中，饮食24小时 从MHS参与者收集的召回将使用更新的 食品和营养数据库，包括跨脂肪酸值（16：1，18：1， 18：2，总计）。 重新计算产生的摄入估计值将是 分析以检查1980年之间反式酸性摄入的时间趋势 和1997年，并检查反式潮流的时间趋势的关系 酸摄入其他饮食和非疾病风险的时间变化 冠心病死亡率的因素和变化。 MHS数据为检查饮食成分提供了独特的机会 直到最近才被公认为是CHD的潜在危险因素。