Fatigue & Gender in Dynamic Stability and Low-Back Pain

疲劳

• 批准号: 6400383
• 负责人: KEVIN P. GRANATA
• 金额: $ 11.41万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6400383
• 关键词: back injury; biomechanics; body composition; clinical research; disease /disorder model; disease /disorder prevention /control; electromyography; fatigue; gender difference; human subject; model design /development; musculoskeletal system; neuromuscular function; neurophysiology; occupational disease /disorder; pain; physical model; posture; reflex; spine; statistics /biometry

Occupationally-related low back disorders (LBDs) are the leading cause of lost work days and the most costly occupational safety and health problem facing industry today. Research concludes the biomechanical stability of the spine plays a significant role in low-back injury and prevention. Stability is achieved through a complex mechanical balance between external load and neuro- physiologic control factors including active muscle stiffness, reaction time and response amplitude. Personal factors such as gender and fatigue contribute to LBD risk because they influence neuromuscular response characteristics and associated stability. Unfortunately, existing analyses of spinal stability ignore the dynamic response characteristics of the neuromuscular system. To control LBD risk, to assure safer gender inclusion in the workplace, to facilitate work/rest and training schedules to prevent fatigue related injury prevention, and to improve clinical and rehabilitation assessment; it is necessary to quantify how neuromuscular response dynamics influence spinal stability. It is also necessary to understand how gender, fatigue and spinal posture influence these neuromuscular control factors and the associated risk of spinal instability. The goal of this research is to quantify dynamic stability of the spine and the influence of gender, fatigue, and spinal posture on musculoskeletal stability. Neuro- physiologic components of dynamic spinal stability, including truck stiffness, reaction time and response amplitude, will be measured form a sudden loading protocol and incorporated into a biomechanical model that will quantify dynamic spinal stability. Empirical measures of spinal stability will be recorded from potential energy protocols published from our laboratory. The experiments are designed to change spinal stability requirements without changing biomechanical equilibrium while observing trunk muscle coactivity associated with the recruitment of stability. These will provide empirical estimates of stability and be employed to validate the dynamic stability model. The influence of gender, fatigue and spinal posture on dynamic stability and neuromuscular response dynamics will be evaluated through each of these protocols. Research has established an epidemiologic link between neuromotor response behavior and LBD risk. The proposed effort represents the first to consider the biomechanics of dynamic neuromotor behavior in the control of spinal stability.

与职业相关的下背部疾病（LBD）是工作日损失的主要原因，也是当今行业面临的最昂贵的职业安全和健康问题。 研究得出结论，脊柱的生物力学稳定性在低背部损伤和预防中起着重要作用。 通过外部负载和神经生理控制因素（包括主动肌肉刚度，反应时间和反应幅度）之间的复杂机械平衡来实现稳定性。 性别和疲劳等个人因素会导致LBD风险，因为它们会影响神经肌肉反应特征和相关的稳定性。 不幸的是，现有的脊柱稳定性分析忽略了神经肌肉系统的动态反应特征。 控制LBD风险，以确保在工作场所中纳入更安全的性别，以促进工作/休息和培训时间表，以防止相关的疲劳相关伤害，并改善临床和康复评估；有必要量化神经肌肉反应动态如何影响脊柱稳定性。 还必须了解性别，疲劳和脊柱姿势如何影响这些神经肌肉控制因素以及脊柱不稳定性的相关风险。这项研究的目的是量化脊柱的动态稳定性以及性别，疲劳和脊柱姿势对肌肉骨骼稳定性的影响。 动态脊柱稳定性的神经生理成分（包括卡车刚度，反应时间和反应幅度）将被测量，形成突然的加载方案，并将其掺入生物力学模型中，该模型将量化动态脊柱稳定性。 脊柱稳定性的经验度量将从我们实验室发表的势能方案中记录下来。 该实验旨在改变脊柱稳定性需求，而无需改变生物力学平衡，同时观察与稳定性募集相关的躯干肌肉共振动。 这些将提供稳定性的经验估计，并用于验证动态稳定模型。 性别，疲劳和脊柱姿势对动态稳定性和神经肌肉反应动力学的影响将通过这些方案进行评估。研究已经建立了神经运动反应行为与LBD风险之间的流行病学联系。 提出的努力代表了第一个在控制脊柱稳定性中考虑动态神经运动行为的生物力学。