RES FACIL: KIDNEY DIS, MINORITY HLTH, CVD

RES FACIL：肾病、少数 HLTH、CVD

• 批准号: 6794479
• 负责人: CHARLES K. FRANCIS
• 金额: $ 37.2万
• 依托单位: CHARLES R. DREW UNIVERSITY OF MED & SCI
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-15 至 2003-09-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6794479
• 关键词: biomedical facility; building /facility design /renovation; clinical research; ethnic group; health science research; kidney disorder; training

DESCRIPTION (provided by applicant): To harness the potential of patient oriented research with a focus towards reducing racial, ethnic, cultural and socioeconomic health disparities, the Drew proposes the construction of a LSC, which would be a state-of-the-art Research Center. The LSC will be a new 40,000 sq. ft., two-story physical structure that is needed to replace existing inadequate clinical research areas. The present application is directed toward phase I of the LSC, that will include construction of the shell and build-out of the first floor for clinical research activities. The existing clinical research areas consist of a six-bed outpatient facility that occupies a small unit in the affiliated county medical facility, several temporary trailers on campus, and a satellite research facility off-campus that houses clinical research programs. Drew has a long-standing tradition of excellence, with an institutional mission to reduce health disparities. Several faculty members have nationally and internationally recognized strengths in areas of clinical investigation such as: 1) complex metabolic disorders (diabetes, hypertension, obesity); 2) HIV; 3) cardiovascular and related diseases; 4) environmental and biobehavioral influences on health; and 5) assessment of cultural and epidemiological factors that influence clinical outcomes. Unfortunately, the lack of adequate space and facilities to provide a cohesive and integrated clinical research environment is an impediment to optimizing research subject participation, maintaining subject adherence, maximizing programmatic efficiency, and supporting growth of clinical investigation. The creation of an integrated clinical research environment will transcend these barriers and advance the accomplishment of high quality National Institutes of Health (NIH)-funded clinical research. The vision of the LSC encompasses clinical investigation in the broad context of both the individual and the community, and will provide a critical environment for innovation, creative thinking, and enhanced inter-disciplinary interactions between clinical scientists. In summary, the Specific Aims of the Drew LSC are to: 1) construct a state-of-art two-story research facility (of which federal funds will support the build-out of the first floor only) that integrates a collaborative interaction of major NIH-funded clinically focused research programs and clinical investigative studies into a unified clinical sciences program; 2) provide an optimal physical environment that will support and enhance student training, federally-funded clinical investigators, and the recruitment of established researchers; and 3) improve the clinical research environment at Drew to facilitate high quality training for junior faculty and postdoctoral trainees dedicated to pursuing clinical investigation, with an emphasis on addressing critical health issues of a growing and culturally diverse nati

描述（由申请人提供）：为了利用以患者为导向的研究的潜力，重点是减少种族、民族、文化和社会经济健康差异，德鲁提出建设 LSC，这将是最先进的研究中心。 LSC 将是一个新的 40,000 平方英尺的两层物理结构，需要取代现有的不足的临床研究区域。本申请针对 LSC 的第一阶段，其中包括外壳的建造和用于临床研究活动的一楼的扩建。现有的临床研究区域包括一个六床位的门诊设施（占据附属县医疗机构的一个小单元）、校园内的几辆临时拖车以及校外一个容纳临床研究项目的卫星研究设施。德鲁有着悠久的卓越传统，其机构使命是减少健康差距。几位教员在临床研究领域拥有国内外公认的优势，例如：1）复杂代谢性疾病（糖尿病、高血压、肥胖）； 2）艾滋病毒； 3）心血管及相关疾病； 4）环境和生物行为对健康的影响； 5）评估影响临床结果的文化和流行病学因素。不幸的是，缺乏足够的空间和设施来提供有凝聚力和综合性的临床研究环境，这阻碍了优化研究受试者参与、保持受试者依从性、最大化计划效率和支持临床研究的发展。综合临床研究环境的创建将超越这些障碍，推动美国国立卫生研究院 (NIH) 资助的高质量临床研究的实现。 LSC 的愿景涵盖个人和社区广泛背景下的临床研究，并将为创新、创造性思维和加强临床科学家之间的跨学科互动提供关键环境。总之，德鲁 LSC 的具体目标是： 1）建造一个最先进的两层研究设施（其中联邦资金将仅支持一楼的建设），该设施整合了NIH 资助的主要临床重点研究项目和临床调查研究纳入统一的临床科学项目； 2）提供最佳的物理环境，以支持和加强学生培训、联邦资助的临床研究人员以及现有研究人员的招募； 3) 改善德鲁的临床研究环境，以促进对致力于临床研究的初级教师和博士后学员进行高质量的培训，重点是解决日益增长和文化多元化的国家的关键健康问题