DEVELOPMENTAL ADAPTATION

发育适应

• 批准号: 6207581
• 负责人: NORMAN J SIEGEL
• 金额: $ 41.04万
• 依托单位: YALE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-03-14 至 2005-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6207581
• 关键词: child physical development; health science research support; medical education; pediatrics; postdoctoral investigator; science education; training

DESCRIPTION (Adapted from the applicant's description): A program of Child Health Research Career Development Awards in the Department of Pediatrics at Yale Universit School of Medicine is designed to provide intensive basic research experience to prepare young pediatric fellows and faculty for productive and independent careers in biomedical research and academic pediatrics. The theme of this proposal, Developmental Adaptation. continues the emphasis established ten years ago with the inception of the Yal Child Health Research Center P30 grant and capitalizes on extant expertise in the Department regarding heart, lung and brain development, ontogeny of the immune response and its interactions with childhood pathogens, an developmental models of hypoxia. This theme also catalyzes productive and on-going collaborations with th Departments of Cell Biology, Genetics, Immunobiology, Molecular Biology and Biophysics, Molecular, Cellular an Developmental Biology, and Physiology; members of each of these departments have places on our Advisor Committee or are listed among our mentors. The proposed program will provide flexible basic research experience and support for young pediatri scientists through collegial interactions with well established senior scientists (mentors), through start-up fundin provided by new project development awards, through the weekly core lectures at the YCHRC, and through cor laboratories in molecular biology and cellular imaging located at the YCHRC. Selection of CHRCDA Scholars continue to be highly competitive and to draw from a replenishing pool of qualified fellows who themselves have undertaken basic research during subspecialty training. Overall, the CHRCDA program intends to build on the past success of the CHRC mechanism and to enhance its productivity by centralization of core facilities and curriculum a the YCHRC, by leveraging the existing interactions among research programs within the institution, and by benefitin from a recruitment base of highly qualified applicants.

描述（改编自申请人的描述）：儿童项目 儿科健康研究职业发展奖 耶鲁大学医学院旨在提供强化基础课程 研究经验为年轻的儿科研究员和教师做好准备 在生物医学研究和学术领域富有成效和独立的职业生涯 儿科。该提案的主题是“发展适应”。继续 十年前随着 Yal Child 的成立而确立的重点 健康研究中心 P30 拨款并利用现有的专业知识 心、肺、脑发育、免疫个体发育科 反应及其与儿童病原体的相互作用，这是一种发育过程 缺氧模型。这个主题还促进了富有成效和持续的 与细胞生物学、遗传学、免疫生物学系合作， 分子生物学和生物物理学，分子、细胞和发育 生物学和生理学；每个部门的成员都在 我们的顾问委员会或被列为我们的导师。 拟议的计划将提供灵活的基础研究经验和 通过与良好的同事互动来支持年轻的儿科科学家 通过以下机构提供的启动资金建立了资深科学家（导师） 新项目开发奖，通过 YCHRC 每周的核心讲座， 并通过位于分子生物学和细胞成像领域的 Cor 实验室 在YCHRC。 CHRCDA学者选拔竞争依然激烈 并从自己拥有的合格人员补充库中进行选拔 在专科培训期间进行基础研究。总体而言，CHRCDA 该计划旨在以 CHRC 机制过去的成功为基础， 通过集中核心设施和课程来提高生产力 YCHRC，通过利用研究项目之间现有的互动 在机构内，并受益于高度的招聘基础 合格的申请人。