COMMUNITY RANDOMIZED TRIAL OF HISPANIC CANCER PREVENTION

预防西班牙裔癌症的社区随机试验

• 批准号: 6418977
• 负责人: BETI THOMPSON
• 金额: $ 0.12万
• 依托单位: FRED HUTCHINSON CANCER RESEARCH CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-07-02 至 2003-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6418977
• 关键词: Hispanic Americans; behavior therapy; behavioral /social science research tag; biomarker; cancer prevention; cancer risk; clinical research; colorectal neoplasms; community health services; diet; dietary fiber; dietary lipid; female; health behavior; health care service utilization; health services research tag; human subject; lifestyle; mass screening; medical outreach /case finding; neoplasm /cancer diagnosis; nutrition aspect of cancer; outcomes research; smoking cessation

DESCRIPTION: Hispanics are the fastest growing minority group in the U.S. and also have the highest poverty rates in the U.S. They have higher rates of certain types of cancer, are less likely to have cancer screening, and tend to have less knowledge about cancer and cancer prevention than Non-Hispanics. Cancer rates are increasing in this group. This application builds on two years of developmental work in a community that is 65 percent to 75 percent Mexican-American. The overall goals of this proposed project are to increase cancer prevention lifestyle behaviors, specifically to decrease fat consumption, increase fruit and vegetable consumption, and increase smoking cessation rates; and to increase colorectal cancer screening. Twenty communities in the lower Yakima Valley, which has a 40 percent to 50 percent Hispanic population, will be recruited for participation. After an in-person randomized household survey of approximately 100 households per community, communities will be matched and randomized within blocks to an intervention or control condition. In intervention communities, a community board will be established, will hire a field coordinator, mobilize the community, and plan intervention activities, with FHCRC staff serving as facilitators, and local project staff hired to assist the Boards. Community-wide events will be conducted to raise consciousness and increase knowledge about cancer prevention and access to screening. These will be pilot-tested in our developmental study community. Individual activities will focus on one-to-one outreach where volunteers and community people will discuss behavior changes that may decrease the risks of contracting cancer. A nested study will be included to assess the efficacy of an intensive, individual intervention to change dietary behavior among groups of women in the intervention communities. After intervention, another cross-sectional survey will be conducted. Primary outcomes are changes in the behaviors defined in the primary aims. A score of combined changes will also be generated. The sample sizes take into account intraclass correlation and are sufficient to examine differences among Hispanics as well as the entire Valley population. The analysis is based on intent to treat.

描述：西班牙裔是美国增长最快的少数群体 而且在美国也有最高的贫困率 在某些类型的癌症中，癌症筛查的可能性较小，并且 对癌症和预防癌症的了解往往比 非西班牙裔。 该组的癌症发生率正在增加。 该应用程序建立在社区的两年发展工作的基础上 那是墨西哥裔美国人的65％至75％。 总体目标 这个拟议的项目是增加预防癌症的生活方式行为， 专门用于减少脂肪消耗，增加水果和蔬菜 消费和增加戒烟率；并增加 结直肠癌筛查。 下亚基马山谷的二十个社区， 将招募有40％至50％的西班牙裔人口 参加。 经过面对面的随机家庭调查 每个社区约有100个家庭，社区将被匹配，并且 在块内随机分配干预或控制条件。 在干预社区中，将建立社区委员会，将 聘请现场协调员，动员社区并计划干预 活动，FHCRC员工担任促进者和本地项目 工作人员雇用为董事会提供帮助。 将举办社区范围的活动 提高意识并增加对预防癌症的知识和 访问筛选。 这些将在我们的发展研究中进行试点测试 社区。 个别活动将集中于一对一的外展 志愿者和社区人员将讨论可能的行为改变 降低患癌症的风险。 将包括一项嵌套研究 评估强化，个人干预改变的功效 干预社区中妇女群体的饮食行为。 干预后，将进行另一项横断面调查。 主要结果是主要目的定义的行为的变化。 还将生成一系列组合更改。 样本量采用 考虑到类内相关性，足以检查 西班牙裔和整个山谷人口之间的差异。 这 分析是基于治疗意图。