GENE THERAPY FOR CERVICAL CARCINOMA

宫颈癌的基因治疗

• 批准号: 6328982
• 负责人: Leaf Huang
• 金额: $ 18.12万
• 依托单位: UNIVERSITY OF PITTSBURGH AT PITTSBURGH
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-10 至 2001-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6328982
• 关键词: DNA directed RNA polymerase; SCID mouse; antisense nucleic acid; apoptosis; athymic mouse; cervix neoplasms; gene expression; gene therapy; genetic enhancer element; genetic promoter element; genetic regulation; human papillomavirus; interleukin 12; messenger RNA; neoplasm /cancer immunology; neoplastic growth; nonhuman therapy evaluation; oligonucleotides; oncoproteins; p53 gene /protein; protein structure function; retinoblastoma protein; ribozymes; transfection /expression vector; virus protein

项目成果

Liposomal atp or NAD+ protects human endothelial cells from energy failure in a cell culture model of sepsis.

在脓毒症细胞培养模型中，脂质体 atp 或 NAD 可保护人内皮细胞免受能量衰竭。

• 发表时间: 2001
• 期刊: Research communications in molecular pathology and pharmacology.
• 作者: Han,YY;Huang,L;Jackson,EK;Dubey,RK;Gillepsie,DG;Carcillo,JA
• 通讯作者: Carcillo,JA

Intraperitoneal administration of pMP6/liposome complexes inhibits the growth of co-localized colon-26 adenocarcinoma cells by inducing a tumor-specific immune response.

腹腔内施用 pMP6/脂质体复合物可通过诱导肿瘤特异性免疫反应来抑制共定位的结肠 26 腺癌细胞的生长。

• 发表时间: 2003
• 期刊: Anticancer research.
• 作者: Sturlan,Sanda;Schneeberger,Achim;Fang,Min;Beinhauer,BrittaG;Luhrs,Petra;Kutil,Raphaela;Wessner,Barbara;Huang,Leaf;Aasen,AnsgarO;Rogy,MichaelA
• 通讯作者: Rogy,MichaelA

Lyophilization of cationic lipid-protamine-DNA (LPD) complexes.

• DOI: 10.1002/(sici)1520-6017(200003)89:3
• 发表时间: 2000-03
• 期刊: Journal of pharmaceutical sciences
• 影响因子: 3.8
• 作者: B. Li;S. Li;Y. Tan;D. Stolz;Simon C Watkins;L. Block;L. Huang

In vivo gene transfer of murine interleukin-4 inhibits colon-26-mediated cancer cachexia in mice.

小鼠白细胞介素 4 的体内基因转移可抑制小鼠结肠 26 介导的癌症恶病质。

• 发表时间: 2002
• 期刊: Anticancer research.
• 作者: Sturlan,Sanda;Beinhauer,BrittaG;Oberhuber,Georg;Huang,Leaf;Aasen,AnsgarO;Rogy,MichaelA
• 通讯作者: Rogy,MichaelA