IDENTIFICATION OF ATRIAL GLAND PEPTIDES IN APLYSIA

海兔心房肽的鉴定

• 批准号: 6308881
• 负责人: EARL MAYERI
• 金额: $ 0.99万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-03-01 至 2002-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6308881
• 关键词: Invertebrata; animal tissue; biological products; biomedical resource; hormones; mental disorders; nervous system; psychology; reproductive system; spectrometry; structural biology

We are investigating the nueronal basis of reproductive behavior in the marine mollusk, Aplysia. As part of this investigation peptides from the atrial gland, located in the reproductive track, have been chemically purified. They are being used in behavioral and physiological experiments to determine their possible roles as pheromones and/or chemical stimuli that are important for understanding the behavior. Mass spectrometry will be used to identify known polypeptides and uncover new ones for further chemical characterization.

我们正在研究生殖行为的神经基础 在海洋软体动物海兔中。 作为本次调查的一部分 来自位于生殖道的心房腺的肽， 已经经过化学纯化。 它们被用于行为和 生理实验以确定它们可能的作用 信息素和/或化学刺激对于 了解行为。 质谱分析将用于 识别已知的多肽并发现新的多肽以进行进一步的化学分析 表征。