Complementary/Alternative Medicine for Vestibulopathy

前庭病的补充/替代医学

• 批准号: 6320527
• 负责人: DAVID E KREBS
• 金额: $ 21.63万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2001
• 资助国家: 美国
• 起止时间: 2001-05-01 至 2003-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6320527
• 关键词: alternative medicine; balance; behavioral /social science research tag; biomechanics; body movement; clinical trials; data collection methodology /evaluation; degenerative motor system disease; electrodes; exercise; functional ability; gait; head movements; human subject; human therapy evaluation; musculoskeletal disorder therapy; nystagmography; outcomes research; performance; psychological concentration; rehabilitation; sensorimotor system

DESCRIPTION (APPLICANT'S ABSTRACT): It is proposed a randomized, blinded, controlled trial comparing vestibular rehabilitation (VR) to Tai Chi. Our overall goal is to explore whether, and if so, how TC can improve functional, dynamic stability in persons with vestibulopathy (VSP). It is hypothesized that the TC group will demonstrate significantly greater improvement in performing functional activities than the VR group. Specific Aims #1: To determine the relative neuro-biomechanical benefits of TC and VR. Sixty subjects will be randomly assigned into either TC instruction or VR. Both treatment groups will receive identical duration treatment once a week for 10 weeks, with supplemental home exercises. It is hypothesized that I) TC improves whole-body dynamic locomotor stability more than does VR; 2) TC improves gait coordination during planned and unplanned obstacle encounters more than does VR; 3) TC improves whole-body speed related movement control more than does VR. #2: To determine which biomechanical measures best demonstrate TC and VR motor control and coordination improvements. It is proposed to quantify VSP patients' motor control and coordination using muscle power flow, gaze (eyehead) stability, and whole-body dynamic stability during standing, locomotion and balance perturbations. It is hypothesized that 1) The TC group will demonstrate power flow more similar to healthy individuals than those receiving VIA during locomotion and balance recovery followingperturbation; 2) The TC group will demonstrate greater improvements in intersegmental movement coordination, which in turn, translates into improved gaze and whole-body stability, than the VR group. #3: A) To determine whether TC improves psychological status, including fear of falling. B) To determine the association between both psychological variables and TCM medical diagnosis, and their predictive value about response to TC or VR. It is hypothesized that TC will improve both fear of falling and other psychological scores more than VR. It will also be diagnosed each patient according to traditional Chinese medicine (TCM) diagnostic categories to determine whether any TCM category is more likely to be associated with improvements in either group. The latter aim is purely exploratory and descriptive in nature.

描述（申请人的摘要）：提出了一个随机，盲目的， 对照试验比较前庭康复（VR）与太极拳。我们的 总体目标是探索TC是否可以改善功能，以及 患有前庭病（VSP）的人的动态稳定性。假设 TC组将在执行方面显着改善 功能活动比VR组。 具体目的＃1：确定TC的相对神经生物力学益处 和VR。六十名受试者将随机分配到TC指令或 VR。两个治疗组将每周接受相同的持续时间治疗 10周，进行补充家庭练习。假设i）TC 与VR相比，改善全身动态运动稳定性。 2）TC 在计划和计划外的障碍遇到期间改善步态协调 超过VR； 3）TC改善全身相关运动控制 超过VR。 ＃2：确定哪种生物力学措施最好 演示TC和VR电动机控制和协调改进。这是 提议使用肌肉量化VSP患者的运动控制和协调 功率流，凝视（眼头）稳定性和全身动态稳定性 站立，运动和平衡扰动。假设1） TC组将展示与健康个体更相似的功率流 那些在移动和平衡恢复期间通过的人 下执性； 2）TC组将显示出更大的改进 段移动协调又转化为改进 与VR组相比，凝视和全身稳定性。 ＃3：a）确定是否 TC改善了心理状况，包括对跌倒的恐惧。 b）确定 心理变量与TCM医学诊断之间的关联， 以及他们对TC或VR响应的预测价值。假设 TC将改善对跌倒和其他心理成绩的恐惧 VR。它也将根据传统中文诊断为每个​​患者 医学（TCM）诊断类别以确定是否有任何TCM类别 更可能与两组的改进相关联。后一个目标 本质上是纯粹的探索性和描述性的。