GENERAL CLINICAL RESEARCH CENTER

全科临床研究中心

• 批准号: 2722810
• 负责人: ANTONIO M GOTTO
• 金额: $ 305.56万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-12-01 至 2003-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2722810
• 关键词: clinical research; human subject

This is a resubmission of a multi-departmental and multi-categorical grant application for the Children's Clinical Research Center (CCRC) at The New York Hospital-Cornell Medical Center, which serves as one of the key focal points for Cornell University Medical College's (CUMC) programs in clinical investigation and in clinical research training. This proposal requests five years of continued support for the Children's Clinical Research Center, where clinical investigators can pursue studies to increase their understanding of normal function and disease mechanisms in humans in an optimal research setting. The Center provides a discrete inpatient unit with 8 research beds and an outpatient facility for child ambulatory research subjects. The current CCRC Hormone Assay Laboratory provides cost effective, non-routine, quality-controlled hormone assays for a diverse number of investigators and projects. We wish to add scientific needs of many new protocols. In addition to serving the research facility of CUMC, the center is also available to clinical investigators at affiliated hospitals, as in inpatient and ambulatory research resource within a high technology, tertiary-care general hospital. Current and projected projects include studies in the areas of endocrinology and metabolism hypertension, hematology, infectious disease, rheumatology, immunology, genetics, neurology, pharmacology, psychiatry, and the relationship of collagen synthesis and connective tissue to disease. Diseases under study utilizing the CCRC resource are complex and often multi-disciplinary in scope, and of considerable biological, medical, and/or public health significance. Based on the critique of the last submission, this application has undergone substantial revisions and all the criticisms have been addressed.

这是为纽约医院康奈尔医学中心儿童临床研究中心 (CCRC) 重新提交的多部门和多类别拨款申请，该中心是康奈尔大学医学院 (CUMC) 的关键焦点之一）临床调查和临床研究培训项目。该提案要求为儿童临床研究中心提供五年的持续支持，临床研究人员可以在最佳研究环境中进行研究，以增进对人类正常功能和疾病机制的了解。该中心提供一个独立的住院病房，设有 8 张研究床位和一个用于儿童流动研究对象的门诊设施。目前的 CCRC 激素检测实验室为众多研究人员和项目提供具有成本效益、非常规、质量控制的激素检测。我们希望添加许多新协议的科学需求。除了为 CUMC 的研究机构提供服务外，该中心还向附属医院的临床研究人员提供服务，例如高科技三级综合医院内的住院和门诊研究资源。目前和预计的项目包括内分泌学和代谢性高血压、血液学、传染病、风湿病学、免疫学、遗传学、神经学、药理学、精神病学以及胶原蛋白合成和结缔组织与疾病的关系等领域的研究。利用 CCRC 资源研究的疾病非常复杂，而且通常涉及多学科范围，并且具有相当大的生物学、医学和/或公共卫生意义。根据上次提交的批评，该应用程序进行了实质性修改，所有批评均已得到解决。