Extraction Protocols for the Life Marker Chip 2009 Q2

生命标记芯片的提取方案 2009 年第 2 季度

• 批准号: ST/H001107/1
• 负责人: Mark Sephton
• 金额: $ 3.5万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2009
• 资助国家: 英国
• 起止时间: 2009 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=ST%2FH001107%2F1
• 关键词: Extraction; Protocols; Life; Marker; Chip

The extraction of organic molecules from samples on Mars and their subsequent delivery to an instrument capable of characterizing their chemistry represents a substantial analytical challenge. Difficulties arise because of the various chemical properties of the target molecules. Biological molecules are predominantly polar and dissolve readily in aqueous solutions whereas fossil organic molecules are non polar and dissolve in organic solvents; abiotic molecules can contain both types. The organic molecules may reside in a number of lithologies each of which can selectively retain certain analytes. These matrix effects represent potential barriers for effective extraction procedures. This work will assess further options for improving sample extraction and analyte concentration, with application to several rock types for the Life Marker Chip.

从火星上的样品中提取有机分子及其随后递送到能够表征其化学的仪器的仪器的挑战。由于目标分子的各种化学性质而出现困难。生物分子主要是极性的，并且在水溶液中易于溶解，而化石有机分子是非极性的，并且溶解在有机溶剂中。非生物分子可以包含两种类型。有机分子可以驻留在许多岩性中，每个岩性都可以选择性地保留某些分析物。这些基质效应代表了有效提取程序的潜在障碍。这项工作将评估改善样品提取和分析物浓度的进一步选择，并将其应用于生命标记芯片的几种岩石类型。