URANIUM MINERS HEALTH STUDY

铀矿工人健康研究

• 批准号: 6279779
• 负责人: FRANK GILLAND
• 金额: $ 2.62万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6279779
• 关键词: cancer risk; chemical carcinogenesis; clinical research; human subject; lung neoplasms; minings; molecular oncology; neoplasm /cancer diagnosis; occupational health /safety; uranium

The purpose of this study is to define the evolution of cellular and molecular changes during respiratory carcinogenesis in former uranium miners. 1) To establish a cohort of former miners at high risk for lung cancer. 2) To prospectively follow this cohort for serial cellular and molecular changes during respiratory carcinogensis. 3) To develop an effective lung cancer screening approach for these high risk former miners.

这项研究的目的是定义细胞和 前铀呼吸道癌期间的分子变化 矿工。 1）建立一个前矿工队列的肺部高风险 癌症。 2）前瞻性遵循该队列的串行细胞和 呼吸道癌期间的分子变化。 3）开发一个 这些高风险的有效肺癌筛查方法以前 矿工。