INTRANODAL INJECTION OF RHGH CSF IN FOLLICULAR SMALL CELL LYMPH NODES

滤泡小细胞淋巴结节内注射 RHGH CSF

• 批准号: 2785513
• 金额: $ 3.4万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/2785513
• 关键词: clinical research; colony stimulating factor; drug adverse effect; drug screening /evaluation; human subject; injection /infusion; lymph nodes; recombinant proteins; somatotropin

This study involves direct injection of recombinant human granulocyte macrophage colony stimulating factor (rhGM-CSF) into lymphomators, lymph nodes, observing toxicity, kinetics of entry of rh-GM-CSF into the circulation, and response. A single patient has received five 21 day cycles of treatment with little toxicity and objective evidence of response.

这项研究涉及直接注射重组人粒细胞 巨噬细胞刺激因子（RHGM-CSF）淋巴淋巴 节点，观察毒性，RH-GM-CSF进入的动力学 循环和反应。 一个患者已收到五个21天 几乎没有毒性和客观证据的治疗周期 回复。