A STUDY TO UNDERSTAND THE EFFECTS OF CORTICOSTEROIDS ON HIV INFECTION

了解皮质类固醇对 HIV 感染影响的研究

• 批准号: 6276142
• 负责人: Thomas M Kerkering
• 金额: $ 3.31万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6276142
• 关键词: HIV infections; clinical research; corticosteroids; cytokine; dendritic cells; drug screening /evaluation; hormone regulation /control mechanism; hormone therapy; human therapy evaluation; microorganism disease chemotherapy; pharmacokinetics; prednisone

The clinical observation that patients improve while receiving prednisone coupled with laboratory evidence for the role of cytokines and follicular dendritic cells in the pathogenesis of HIV infection and knowing of prednisones action on both of the elements warrants the need to study and understand the role of prednisone in HIV infection.

患者在接受泼尼松时会有所改善的临床观察结果 再加上细胞因子和卵泡作用的实验室证据 树突状细胞在艾滋病毒感染的发病机理中和知道 对这两个元素的泼妇行动都需要学习和 了解泼尼松在HIV感染中的作用。