CORE--ANIMALS

核心——动物

• 批准号: 6267128
• 负责人: KATHLEEN H MCDONOUGH
• 金额: $ 14.7万
• 依托单位: LSU HEALTH SCIENCES CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-12-01 至 1998-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6267128
• 关键词: alcoholism /alcohol abuse; animal care; animal colony; biomedical facility; disease /disorder model; laboratory rat; model design /development

The Animal Resource Laboratory is one of the Alcohol Research Center's Core Laboratories. The long-term goal of this Core is to serve as a central facility through which investigators can obtain well controlled and reproducible animal models, and receive training related to in vivo experimentation. It is envisaged that the Animal Core will enhance experimental productivity in alcohol research by achieving four specific aims: (1) to provide space, technical assistance (both surgical and experimental), equipment, and supplies for pre- an post-operative animal care; (2) to produce a well controlled and reproducible rodent model of chronic alcohol consumption; (3) to train and teach new investigators, students,and technicians the basic surgical and experimental skills required for whole animal research (educational component); and (4) to develop new models, techniques and experimental approaches when needed, and thereby broaden the surgical and experimental procedures available to investigators. The Animal Resource Core will be primarily used for investigators that have a Research Component, Pilot study supported by the Alcohol Research Center and/or a project supported by NIAAA that is related to the overall theme and objectives of the LSUMC Alcohol Research Center. By providing the above mentioned services the Animal Resources Laboratory will be able to substantially lower the expense of the proposed research both in time and money, reduce experimental variability and ensure animal welfare.

动物资源实验室是酒精研究中心的实验室之一 核心实验室。 该核心的长期目标是作为 调查人员可以通过中央设施获得良好的控制 和可重复的动物模型，并接受与体内相关的培训 实验。 预计动物核心将增强 通过实现四个特定的目标，提高酒精研究的实验效率 目标：(1) 提供空间、技术援助（包括手术和技术援助） 手术前动物的实验）、设备和用品 关心; (2) 制作良好控制且可重复的啮齿动物模型 长期饮酒； (3) 培训和教导新的研究者， 学生和技术人员基本的手术和实验技能 整个动物研究所需（教育部分）； (4) 至 需要时开发新模型、技术和实验方法， 从而扩大可用的手术和实验程序 给调查人员。 动物资源核心将主要用于 具有研究部分、试点研究支持的研究人员 酒精研究中心和/或 NIAAA 支持的项目 与 LSUMC 酒精研究的总体主题和目标相关 中心。 通过提供上述服务，动物资源 实验室将能够大幅降低费用 提出时间和金钱的研究，减少实验变异性 并确保动物福利。