EFFECTS OF NUTRITIONAL INTERVENTION ON PROTEIN BREAKDOWN IN CRITICALLY ILL CHILD

营养干预对危重儿童蛋白质分解的影响

• 批准号: 6118774
• 负责人: ROBERT KATZ
• 金额: $ 2.24万
• 依托单位: UNIVERSITY OF NEW MEXICO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6118774
• 关键词: child (0-11); clinical research; dietary aminoacid; dietary carbohydrates; dietary constituent; digestion; glucose; hormone regulation /control mechanism; human subject; insulin; nutrition; nutrition related tag; proteolysis

Our hypothesis is that the increased levels of insulin induced by the glucose infusion should effect a decrease in protein breakdown. Since it appears that the effect of insulin on suppression of proteolysis is limited by the decrease in amnio acids, the patients that receive glucose plus amino acids should demonstrate more suppression of proteolysis.

我们的假设是，葡萄糖输注诱导的胰岛素水平的增加应影响蛋白质分解的降低。 由于胰岛素对蛋白水解抑制的影响似乎受羊膜酸的降低受到限制，因此接受葡萄糖加氨基酸的患者应表现出更多抑制蛋白水解。