ACTIVATION OF CD28 NEGATIVE T CELLS IN RHEUMATOID ARTHRITIS

类风湿性关节炎中 CD28 阴性 T 细胞的激活

• 批准号: 6115666
• 负责人: Nancy J Olsen
• 金额: $ 3.64万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6115666
• 关键词: CD28 molecule; clinical research; helper T lymphocyte; histocompatibility gene; human subject; leukocyte activation /transformation; pathologic process; rheumatoid arthritis

Determine the relationship between expansion of CD38-CD4+T cells, HLA alleles, and Rheumatoid Arthritis (RA) and whether CD28-CD4+T cell are pathogenic importance in RA and related to disease activity. We are in the recruiment and enrollment phase and are continuing with this focus.

确定CD38-CD4+T细胞的扩展HLA之间的关系 等位基因，类风湿关节炎（RA）以及CD28-CD4+T细胞是否是 病原的重要性在RA中，与疾病活动有关。 我们处于新兵和入学阶段，继续 这个重点。