CORE--METHODOLOGY AND DATA MANAGEMENT

核心——方法论和数据管理

• 批准号: 6235690
• 负责人: Alan R Dyer
• 金额: $ 15.69万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-02-01 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6235690
• 关键词: analytical method; biomedical facility; computer program /software; computer system hardware; data collection methodology /evaluation; data management; human data; information systems; osteoarthritis; population survey; rheumatoid arthritis; statistical service /center; systemic lupus erythematosus

The Methodology and Data Management Core is critically important to the success of this MAMDC and its EEHSR Component in particular. The centralized availability of expertise in database and study form construction; data entry, monitoring, and retrieval, and the various analytic techniques used to test hypotheses and control for potential confounders are essential resources for all investigators. The Core has assisted educators, epidemiologists, and health services researchers from several divisions and departments in studying a wide variety of disease and demographic groups including systemic lupus erythematosus, osteoarthritis, juvenile dermatomyositis (JDMS), rheumatoid arthritis, and the elderly. Core resources have been used efficiently because of the economies of scale in addition to excellent coordination with the EEHSR component. Recognizing that newer analytic techniques have become available and more accepted and that this proposal represents an expansion of our work in clinical epidemiology and health services research, this proposed Core is both larger to support a greater volume of work and broader t utilize these new analytic techniques. As a result of the Executive Committee's decision to emphasize longitudinal and cost-effectiveness research, experts in advanced statistical techniques (generalized estimating equation (GEE), classification and regression trees (CART), econometric approaches to controlling selection bias, meta-analysis), economics, and decision analysis (stochastic tree modeling, continuous- risk utility assessment) have been recruited as Core co-investigators. Clinical Epidemiology has also been formally included within the Core structure. The Core will support the four EEHSR proposals in this grant application and the funded activities of the JDMS registry and Children's Memorial Hospital. It will continue to contribute to the MAMDC research environment by providing data management and methodologic assistance to investigators who engage in arthritis related research. The institution of a EEHSR/Core research conference and enhanced viability and support for health services research on Northwestern University's Chicago Campus will further heighten the Core's influence on the environment.

方法和数据管理核心非常重要 为此MAMDC及其EEHSR组件的成功 特别的。数据库中的专业知识的集中可用性 研究形式的建设；数据输入，监视和检索，以及 用于检验假设和控制的各种分析技术 潜在的混杂因素是所有研究人员的重要资源。 这 核心已协助教育者，流行病学家和卫生服务 来自多个部门和部门的研究人员研究广泛 variety of disease and demographic groups including systemic lupus 红斑，骨关节炎，青少年皮肌炎（JDMS）， 类风湿关节炎和老年人。 核心资源已被使用 有效，由于规模经济，除了优秀 与EEHSR组件的协调。 认识到这个新的 分析技术已变得可用，更被接受，并且 该提案代表了我们在临床方面的研究 流行病学和卫生服务研究，这一提议的核心都是 较大以支持大量的工作，并更广泛地利用这些工作 新的分析技术。由于执行委员会的结果 强调纵向和成本效益研究的决定， 高级统计技术的专家（广义估计 等式（GEE），分类和回归树（购物车）， 控制选择偏见的计量经济学方法，荟萃分析）， 经济学和决策分析（随机树建模，连续 - 风险公用事业评估）已被招募为核心共同投资者。 临床流行病学也已正式包括在核心中 结构。 核心将支持这四个EEHSR建议 授予申请和JDMS注册表的资助活动以及 儿童纪念医院。 它将继续为 MAMDC研究环境通过提供数据管理和 对参与关节炎相关的研究人员的方法学帮助 研究。 EEHSR/核心研究会议的机构和 增强了生存能力和对卫生服务研究的支持 西北大学的芝加哥校园将进一步提高 核心对环境的影响。