ALVEOLAR MACROPHAGES AND AIDS

肺泡巨噬细胞和艾滋病

• 批准号: 6246402
• 负责人: ELIZABETH A RICH
• 金额: $ 1.98万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246402
• 关键词: AIDS; HIV infections; alveolar macrophages; bronchoscopy; cellular pathology; clinical research; host organism interaction; human immunodeficiency virus; human subject; microorganism immunology; virus replication

To examine the functions of alveolar macrophages from a spectrum of HIV infected patients and to quantitate the level of HIV in these cells. To examine determinants of replication of HIV in alveolar macrophages and the mechanisms underlying the functional consequences of HIV infection in macrophages. Bronchoscopies are performed on the GCRC to obtain cells used in this study.

检查来自HIV谱的肺泡巨噬细胞的功能 感染患者并定量这些细胞中的HIV水平。 到 检查肺泡巨噬细胞中HIV复制的决定因素和 HIV感染功能后果的基础机制 巨噬细胞。在GCRC上进行支气管镜检查以获得所用的细胞 在这项研究中。