DIET INTERVENTION AND CLINICAL OUTCOMES IN PHENYLKETONURIA

苯丙酮尿症的饮食干预和临床结果

• 批准号: 6246295
• 负责人: BOBBYE M ROUSE
• 金额: $ 2.71万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-01-06 至 1997-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6246295
• 关键词: child (0-11); child physical development; clinical research; developmental nutrition; diet therapy; disease /disorder prevention /control; disease /disorder proneness /risk; female; gene mutation; genotype; human genetic material tag; human pregnant subject; human subject; human therapy evaluation; longitudinal human study; mother /embryo /fetus nutrition; mother /infant health care; nutrition related tag; phenylketonurias; pregnancy

Early diagnosed and treated infants with PKU will have normal growth and development. Women with PKU who are treated prior to and during pregnancy will have pregnancy outcomes comparable to nonPKU women. Children with PKU and childbearing women are monitored nutritionally, biochemically, physically and developmentally to test these hypotheses and to establish a standard of care for this disorder.

早期诊断和治疗的PKU婴儿将具有正常的生长，并且 发展。 PKU的妇女在之前和期间接受治疗 怀孕的怀孕结局与非PKU妇女相当。 PKU和生育妇女的儿童受到营养监测， 生化，物理和发展以检验这些假设 并为这种疾病建立护理标准。