HIV INHIBITORY FACTORS IN HUMAN SALIVA

人类唾液中的艾滋病毒抑制因子

• 批准号: 6244382
• 负责人: Daniel Malamud
• 金额: $ 2.36万
• 依托单位: UNIVERSITY OF PENNSYLVANIA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-03-17 至 1998-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6244382
• 关键词: antiAIDS agent; clinical research; communicable disease control; genetic library; host organism interaction; human immunodeficiency virus; human subject; inhibitor /antagonist; protein purification; protein structure; saliva; salivary glands; submandibular gland; virus protein; xerostomias

Characterization of the interaction between salivary factor(s) and HIV, and purify the HIV-inhibitory proteins from human submandibular saliva. Work will continue to screen a submandibular gland cDNA library to identify clones expressing the protein and to determine if xerostomia is associated with decreased anti-HIV activity. (Core O.F. Lab.)

唾液因子和艾滋病毒之间相互作用的表征， 并从人类下颌唾液中净化HIV抑制性蛋白质。 工作将继续将下颌腺cDNA库筛选到 识别表达蛋白质的克隆并确定静脉 与抗HIV活性降低有关。 （Core O.F. Lab。）