CORE--FLOW CYTOMETRY RESOURCE

核心--流式细胞术资源

基本信息

批准号：
6101675
负责人：
ANDREW BERGER
金额：
$ 34.07万
依托单位：
FRED HUTCHINSON CANCER RESEARCH CENTER
依托单位国家：
美国
项目类别：
财政年份：
1999
资助国家：
美国
起止时间：
1999-01-01 至 1999-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/6101675
关键词：
biomedical equipment resource biomedical facility flow cytometry human tissue method development

biomedical equipment resource biomedical facility flow cytometry human tissue method development

项目摘要

The Flow Cytometry laboratory functions as a shared resource for cell analysis and sorting. The resource supports research within all scientific divisions at the FHCRC. The laboratory assists a wide range of investigator-directed research from clinically related studies of primary malignant cells and their normal counterparts, stem cells and gene therapy, to fundamental studies of developmental biology, gene regulation, and neoplastic transformation. The resource supports population-based studies of genomic instability and changes in human solid tumors, reflecting the continued evolution of novel approaches being used by FHCRC investigators. Since its inception in 1978, the resource has continued to enhance its instrumentation, sophistication of usage, and overall level of use. The laboratory continues to maintain its College of American Pathology accreditation for clinically-related investigation. In addition to the maintenance and upgrade of resource equipment, the Flow Cytometry Laboratory actively assists investigators and their laboratories in experimental design, sample preparation, development of novel techniques, analysis and interpretation of data, and training in the operation of the instrumentation. It fulfills an essential role for many peer-reviewed funded research projects as described in this proposal.

流式细胞仪实验室充当单元的共享资源分析和分类。资源支持所有科学的研究 FHCRC的分裂。实验室协助研究者的指导研究来自临床相关研究的研究恶性细胞及其正常对应物，干细胞和基因治疗，用于发展生物学，基因调节的基础研究，和肿瘤转化。资源支持基于人群的研究基因组不稳定性和人类实体瘤的变化，反映FHCRC使用的新方法的持续演变调查人员。自1978年成立以来，该资源一直在继续增强其仪器，使用的精致和整体水平使用。实验室继续维持其美国学院临床相关研究的病理认证。此外为了维护和升级资源设备，流式细胞仪实验室积极协助研究人员及其实验室实验设计，样品制备，新技术的发展，数据的分析和解释，以及在运作中的培训仪器。它履行许多同行评审的重要角色如本提案所述，资助了研究项目。