CORE--HUMAN RESOURCES

核心——人力资源

• 批准号: 6104969
• 负责人: IRL HIRSCH
• 金额: $ 18.1万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-03-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6104969
• 关键词: atherosclerosis; biomedical facility; diabetic angiopathy; diabetic nephropathy; histopathology; immunocytochemistry; in situ hybridization; pathologic process; patient /disease registry; postmortem; tissue resource /registry

The local DCCT/EDIC Cohort Core (Core B1) is designed to make available samples (plasma, lipoproteins and urine) from carefully characterized subjects being followed in the Seattle cohort of the EDIC for use by investigators in the individual projects. The Arterial Tissue and Applied Pathology Core (Core B2) is designed to enhance the scientific objectives and cost-effectiveness of the Program Project in two ways: 1) by providing a centralized repository for diabetic and non-diabetic arterial tissue to be used in tissue-based analyses and 2) by performing specialized tissue- based analyses, including histologic, immunohistochemical (IHC), and in situ hybridization (ISH) studies, as required by the individual projects. Centralizing and standardizing tissue collection will ensure uniformity collection and preservation of samples. Performing histologic and not compel individual projects to develop technical expertise in these areas. Further, carrying out these studies at a single site will allow the results to be made available to each project in a way that facilitates Project interaction

本地DCCT/EDIC队列核心（Core B1）旨在提供可用 精心表征的样品（血浆，脂蛋白和尿液） 在EDIC的西雅图队列中遵循的受试者供其使用 各个项目的调查人员。 动脉组织并应用 病理核心（核心B2）旨在增强科学目标 和计划项目的成本效益通过两种方式：1）通过提供 糖尿病和非糖尿病动脉组织的集中库 用于基于组织的分析和2）进行专业组织 基于组织学，免疫组织化学（IHC）和基于基于的分析 根据各个项目的要求，原位杂交（ISH）研究。 集中和标准化组织收集将确保均匀性 采集和保存样品。 进行组织学而不是 强迫各个项目在这些领域发展技术专长。 此外，在一个地点进行这些研究将允许结果 以促进项目的方式向每个项目提供 相互作用