PREVENTION OF PTSD IN ADULT BURN PATIENTS

预防成年烧伤患者的创伤后应激障碍

• 批准号: 6196368
• 负责人: JOANN DIFEDE
• 金额: $ 21.19万
• 依托单位: WEILL MEDICAL COLL OF CORNELL UNIV
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-15 至 2003-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6196368
• 关键词: behavioral /social science research tag; burns; clinical research; cognition; coping; counseling; disease /disorder prevention /control; human subject; human therapy evaluation; posttraumatic stress disorder; psychological tests; psychotherapy; questionnaires; social support network

This study which, is being submitted in response to PA-99-134 a request for Exploratory/Developmental Grants (R21) for Mental Health Intervention Research, will be conducted at the New York Presbyterian Hospital Regional Burn Center which offers a large heterogeneous population representing both minorities (40 percent) and women (25 percent), where 41 percent of injuries are work-related, and where an alliance between the surgical staff and proposed research team have been well established. Though studies suggest rates of chronic PTSD as high as 45 percent one-year post-burn, there have been no treatment studies of PTSD following burns nor have there been any studies attempting to prevent PTSD in burn patients through early intervention. The principle aim of this study is to adapt, implement, and evaluate a program for the prevention of chronic PTSD in burn survivors. To accomplish these goals, adults consecutively admitted to the Burn Center will be screened for severe PTSD symptoms and Acute Stress Disorder (ASD) within two weeks of their injury. Those with severe PTSD symptoms or a diagnosis of ASD will undergo a comprehensive clinical assessment including the SCID, CAPS, PTSD- SS and a battery of self-report questionnaires that assess social support, coping style, cognitive schemas, ASD and PTSD symptoms. Participants will be randomized to either the prevention program or a supportive counseling control condition (SC). Those in the BP will receive four two-hour prevention sessions. These sessions will be comprised of four techniques psychoeducation, relaxation training, prolonged exposure to traumatic memories, and cognitive restructuring that have proven effective for reducing both severe acute and chronic PTSD symptoms in rape, criminal assault, and motor vehicle accident survivors. To determine the efficacy of the intervention, rates of PTSD and severity of PTSD symptoms in the BP will be compared to rates and severity of symptoms in the SC control condition. Among those burned at work, time to return to work will be compared between the two groups. Results may help fill a gap in the existing literature regarding the efficacy of early intervention for the prevention of PTSD in burn patients. Results will also provide preliminary data on the cost-effectiveness of an early intervention program.

这项研究将在响应PA-99-134提交的研究请求探索/发展赠款（R21），以进行心理健康干预研究，将在纽约长老会医院地区烧伤中心进行，该中心提供大量代表的异质人群少数民族（40％）和妇女（25％），其中有41％的伤害与工作有关，并且在手术人员和拟议的研究小组之间建立了联盟。尽管研究表明，燃烧后燃烧后一年一年的慢性PTSD率高达45％，但在烧伤后没有对PTSD进行的治疗研究，也没有任何研究试图通过早期干预来预防烧伤患者的PTSD。 这项研究的主要目的是适应和评估预防烧伤幸存者慢性PTSD的计划。为了实现这些目标，将在受伤后的两周内筛选出严重的PTSD症状和急性应激障碍（ASD）的成年人将被筛选出严重的PTSD症状和急性应激障碍（ASD）。 患有严重PTSD症状或ASD诊断的人将接受全面的临床评估，包括SCID，CAPS，PTSDSS和一系列评估社会支持，应对方式，认知模式，ASD和PTSD症状的自我报告问卷。参与者将被随机分配为预防计划或支持性咨询控制条件（SC）。 BP中的人将接受四个两个小时的预防课程。 这些会议将包括四种技术，心理教育，放松训练，长期暴露于创伤性记忆以及认知重组，这些技术已证明有效地减轻了强奸，犯罪袭击中的严重急性和慢性PTSD症状，以及汽车车辆事故幸存者。为了确定干预措施的疗效，将将BP中PTSD和PTSD症状的严重程度与SC对照条件下的症状率和严重程度进行比较。 在工作中被烧毁的人中，将在两组之间进行比较。结果可能有助于填补有关早期干预预防PTSD在烧伤患者中的疗效的现有文献的空白。 结果还将提供有关早期干预计划成本效益的初步数据。