MATERNAL DISTRESS, COGNITIVE PROCESSING & PEDIATRIC BMT

产妇痛苦、认知处理

• 批准号: 6165199
• 负责人: William H Redd
• 金额: $ 50.61万
• 依托单位: ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-05-01 至 2003-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6165199
• 关键词: adolescence (12-20); behavioral /social science research tag; bone marrow transplantation; caregivers; child (0-11); clinical research; cognition; coping; functional ability; hospital length of stay; human subject; interview; longitudinal human study; maternal behavior; mother child interaction; neoplasm /cancer therapy; neural information processing; pediatric neoplasm /cancer; postoperative state; psychological adaptation; psychological stressor; social psychology; social support network

DESCRIPTION (Adapted from the Applicant's Abstract): The proposed research will investigate the role of cognitive/social processing in maternal distress associated with pediatric bone marrow transplantation (BMT) in the treatment of pediatric cancer. Although heightened levels of distress among these mothers has been documented in clinical studies, little is known about the course of such distress during and after BMT or factors that place mothers at increased risk for adjustment problems. The research is guided by the integration of current models of cognitive/social processing. According to these models, the psychosocial impact of severe negative life events is related to how well the individual is able to integrate the event into his/her beliefs. This recovery process can be stifled when social constraints on talking about the event exist. In the proposed longitudinal analysis 509 mothers will be recruited to participate in a series of five structured interviews during the course of their child's BMT. Assessments of psychosocial and background factors will be conducted two weeks before BMT hospitalization, during the acute BMT hospitalization, and at 6, 12, and 18 months post-BMT. Specific aims are to: 1) examine the course of psychological distress among mothers of children undergoing BMT; 2) determine the role of cognitive and social processing in the development and maintenance of mothers' psychological distress during and after their children's BMT; and 3) assess how dispositional optimism, monitoring coping style, and prior negative life events influence mothers' cognitive processing and development/maintenance of psychological distress. A combination of latent growth curve and structural equation modeling will be used in the data analysis.

描述（根据申请人的摘要改编）：拟议的研究 将研究认知/社会处理在母亲中的作用 与小儿骨髓移植（BMT）相关的困扰 小儿癌的治疗。 虽然遇到的苦难程度更高 这些母亲在临床研究中已被记录在临床研究中，对 在BMT期间和之后的这种困扰或所处的因素的过程 母亲面临调整问题的风险增加。 该研究是指导的 通过当前认知/社会处理模型的整合。 根据这些模型，严重负面生活的心理社会影响 事件与个人能够整合事件的能力如何 进入他/她的信仰。 当社交时，这种恢复过程可能会被扼杀 关于谈论事件的限制存在。 在拟议的纵向中 分析509位母亲将被招募参加五个 在孩子的BMT过程中进行结构化访谈。 评估 将在两周前进行社会心理和背景因素 BMT住院，在急性BMT住院期间以及6、12和 BMT后18个月。 具体目的是：1）检查 经历了BMT的儿童母亲的心理困扰； 2） 确定认知和社会处理在发展中的作用， 维护母亲在母亲期间和之后的心理困扰 儿童BMT； 3）评估性格乐观，监视应对方式 风格和先前的负面生活事件会影响母亲的认知 心理困扰的处理和发展/维护。 一个 潜在生长曲线和结构方程建模的组合将是 用于数据分析。