PEDIATRIC NEPHROLOGY TRAINING

儿科肾脏病学培训

• 批准号: 6176288
• 负责人: MICHEL GERARD BAUM
• 金额: $ 4.19万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-08-01 至 2001-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6176288
• 关键词: PEDIATRIC; NEPHROLOGY; TRAINING

The purpose of the training program in Pediatric Nephrology at the University of Texas Southwestern Medical Center is to train pediatricians for careers as independent investigators in academic Pediatric Nephrology. There is a shortage of Pediatric Nephrologists in the United States and many positions in Pediatric Nephrology go unfilled each year. Most trainees in Pediatric Nephrology do not receive training to prepare them for independent research careers. This application requests funds for two Pediatric Nephrology fellowship positions per year (clinical training is paid by the Department of Pediatrics). Fellows will spend at least two years in laboratories whose interests include: 1)renal developmental physiology; 2) signal transduction; 3) regulation of proximal tubule NaCl transport; 4) pathogenesis of renal tubular acidosis; 5) citrate transport and metabolism; 6) molecular mechanisms of proximal tubule acidification and phosphate transport; 7) the effect of ischemia in renal transplant rejection and the mechanism for macrophage activation; 8) role of heat shock proteins in acute renal failure; 9) pathogenesis of hypertension. In addition, fellows attend weekly conferences given by the Department of Pediatrics designed to prepare fellows for careers in academic medicine. Topics covered include statistics, use of Computers in biomedical research, how to write a manuscript and grant, and use of animals and humans in research. Topics related to ethics in medicine and biomedical research are strongly emphasized in these lectures and additional medical ethics lectures are also given by the University for fellows. Joint weekly conferences by the Divisions of Pediatric and Internal Medicine Nephrology include clinical and molecular biology journal clubs, renal grand rounds, renal research conference, and a renal physiology lecture series. Fellows also attend seminars in basic science departments. Trainees are closely supervised by their research mentor as well as the P.I. to insure that the goals of this training program are achieved.

小儿肾脏病学培训计划的目的 德克萨斯大学西南医学中心将培训儿科医生 作为学术儿科肾病学独立调查员的职业。 美国缺乏儿科肾病专家 每年小儿肾病科都有许多职位空缺。最多 小儿肾脏病学的学员没有接受准备培训 为独立研究事业。该申请要求为两个人提供资金 每年小儿肾病学研究金职位（临床培训是 由儿科支付）。 研究员将花费至少两个 在实验室工作多年，兴趣包括：1）肾脏发育 生理; 2）信号转导； 3）近曲小管NaCl的调节 运输; 4）肾小管性酸中毒的发病机制； 5) 柠檬酸盐运输 和新陈代谢； 6）近曲小管酸化的分子机制 和磷酸盐运输； 7）缺血对肾移植的影响 排斥反应和巨噬细胞激活机制； 8）热的作用 急性肾功能衰竭中的休克蛋白； 9）高血压的发病机制。 此外，研究员还参加由该部举办的每周会议 儿科旨在帮助研究员为学术医学职业做好准备。 涵盖的主题包括统计学、计算机在生物医学中的使用 研究，如何撰写手稿和资助，以及动物和动物的使用 人类在研究中。与医学和生物医学伦理相关的主题 这些讲座和其他医学课程都强调研究 大学还为研究员举办道德讲座。联合周刊 儿科和内科肾病科会议 包括临床和分子生物学期刊俱乐部、肾脏大轮次、 肾脏研究会议和肾脏生理学系列讲座。研究员 还参加基础科学部门的研讨会。学员们紧密地 由他们的研究导师和 P.I. 监督。以确保 本次培训计划的目标已达到。