Exotic isotope production for medical applications

用于医疗应用的奇异同位素生产

• 批准号: MR/X036561/1
• 负责人: Thomas Day Goodacre
• 金额: $ 201.25万
• 依托单位: University of Manchester
• 依托单位国家: 英国
• 项目类别: Fellowship
• 财政年份: 2024
• 资助国家: 英国
• 起止时间: 2024 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FX036561%2F1
• 关键词: Exotic; isotope; production; medical; applications

Radioactive isotopes have ratio of protons and neutrons that results in their instability. This presents both a plethora of opportunities, and a challenge to obtain them due to their finite nature. This work seeks to meet the rising medical demand for these exotic isotopes, through the development of new technologies and approaches for radioactive isotope production and separation. While the use of established medical isotopes is growing, there are challenges to the supply as nuclear research reactors are decommissioned across the world. Additionally, the application of non-standard isotopes such as 225Ac have shown significant promise for the treatment of cancers, while others have applications in medical imaging. Reliable processes for the production and separation of these isotopes are required to realise the full potential of these applications and to produce pre-clinical amounts for initial studies. This work seeks to address this through ion source and electromagnetic mass separator development for exotic medical isotope production.

放射性同位素的质子和中子之比导致其不稳定。这既带来了大量的机会，也带来了由于其有限性而获得这些机会的挑战。这项工作旨在通过开发放射性同位素生产和分离的新技术和方法来满足对这些外来同位素不断增长的医疗需求。尽管现有医用同位素的使用量在不断增长，但随着世界各地核研究反应堆的退役，供应面临着挑战。此外，225Ac 等非标准同位素的应用在癌症治疗方面显示出巨大的前景，而其他同位素则在医学成像方面有应用。需要可靠的生产和分离这些同位素的工艺，以充分发挥这些应用的潜力并生产用于初步研究的临床前数量。这项工作旨在通过开发用于奇异医用同位素生产的离子源和电磁质量分离器来解决这个问题。