BIOBEHAVIORAL ETIOLOGY OF CHRONIC TEMPOROMANDIBULAR

慢性颞下颌关节紊乱病的生物行为病因学

• 批准号: 6176642
• 负责人: James Ryan Fricton
• 金额: $ 21.23万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-01 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6176642
• 关键词: analgesics; central nervous system; chronic disease /disorder; clinical research; coping; depression; disease /disorder etiology; disease /disorder proneness /risk; fibromyalgia; human subject; longitudinal human study; oral facial pain; oral pharyngeal disorder; oral pharyngeal disorder diagnosis; oral pharyngeal surgery; pathologic process; peripheral nervous system; psychological models; psychometrics; questionnaires; statistics /biometry; temporomandibular joint syndrome

This research proposal is designed to determine which central and peripheral factors are involved in the etiology of chronic dysfunctional TMS. This study is a prospective observational cohort study in which baseline jaw dysfunction, oral habits, depression, and fibromyalgia are the primary risk factors to be evaluated for their prognostic importance in the development of chronic dysfunctional pain in temporomandibular disorders. The study design is a 3-year cohort study of 500 non-chronic TMD pain patients who will be followed at 18 and 36 months to determine which subjects develop chronic pain and the influence that these factors have in predicting development. These patients will meet Research Diagnostic Criteria (RDC) axis II Chronic Pain Grading system I or II and have a physical diagnosis of myofacial pain and/or temporomandibular joint (TMJ) disc displacement. Examination data will include the standardized exam of the RDC/TMD axis I, Craniomandibular Index, an occlusal index, and a tender point exam to screen for possible fibromyalgia. Questionnaires will include RDC/TMD axis I and II, coping strategies questionnaire, a self report fibromyalgia screening form, and IMPATH.

该研究建议旨在确定哪个中央和 慢性功能障碍的病因涉及外围因素 TMS。 这项研究是一项前瞻性观察队列研究，其中 基线下颌功能障碍，口腔习惯，抑郁和纤维肌痛是 要评估其预后的主要风险因素 在慢性功能障碍疼痛发展中的重要性 颞下颌疾病。 研究设计是一个3年的队列 研究500名非智TMD疼痛患者 18个月和36个月以确定哪些受试者会出现慢性疼痛 以及这些因素在预测发展中的影响。 这些患者将符合研究诊断标准（RDC）轴II 慢性疼痛分级系统I或II，并具有物理诊断 肌膜疼痛和/或颞下颌关节（TMJ）椎间盘 位移。 考试数据将包括标准化考试 RDC/TMD轴I，颅骨指数，咬合指数和 筛选可能的纤维肌痛的招标点考试。 问卷将包括RDC/TMD轴I和II，应对策略 问卷，一个自我报告的纤维肌痛筛查表和Impath。