FASEB SUMMER CONFERENCE--THE TETRASPANINS SUPERFAMILY

FASEB 夏季会议——四跨膜蛋白超家族

• 批准号: 6189423
• 负责人: Shoshana Levy
• 金额: $ 0.6万
• 依托单位: FEDERATION OF AMER SOC FOR EXPER BIOLOGY
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-07-01 至 2001-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6189423
• 关键词: biological signal transduction; cell adhesion; cell motility; meeting /conference /symposium; nerve /myelin protein; protein structure function; travel

DESCRIPTION (Applicant's Description): This application seeks partial funding for the FASEB 2000 Summer Research Conference on Tetraspanins to be held July 4-July 6 2000 in Snowmass Village, Colorado. This is the first conference ever to be dedicated to this particular superfamily of proteins. This superfamily includes a large number of evolutionarily conserved and ubiquitously expressed genes. Tetraspanins have been implicated in basic biological processes such as cell proliferation, adhesion and motility, membrane fusion and tumor metastasis. This is a relatively new field of research as the first members of this family were identified only a decade ago. The interest in the family has been growing rapidly with new members being identified in a wide range of species including mammals, nematodes, drosophila and Schistosomes. Moreover, known members are being rediscovered continuously by a variety of functional assays. For example, one member of the family was identified last year as the putative receptor for hepatitis c virus. Because of the involvement of tetraspanins in multiple cellular activities, researchers in this field come from different scientific disciplines including immunology, neurobiology, adhesion, cancer research, and virology. To date, communications in this field have been limited to publications, exchange of reagents, and to occasional contacts between individual scientists. This conference is the inaugural tetraspanin research meeting where all interested scientists will meet in person. This will be extremely beneficial for future collaborative studies focused on understanding the mechanism of action of this superfamily of proteins. Purpose of the Conference: 1. To assemble investigators working in this rapidly evolving field to meet each other, to present unpublished data and to discuss questions unique to our field. The conference is aimed at bringing together senior scientists, some with long-term involvement, and newcomers to the field who have encountered tetraspanins in unrelated fields of research. An important mission of this conference is to give an opportunity to junior scientists to present unpublished studies via an abstract-driven presentation mechanism. 2. To stimulate future interactions among investigators from diverse disciplines 3. To identify experimental approaches to unsolved questions in the field. 4. To tackle nomenclature issues. 5. To summarize the current knowledge of the field in an updated review to be published in a high profile scientific journal.

描述（申请人的描述）：本申请寻求部分资金 对于将于7月举行的Faseb 2000夏季研究会议 2000年7月6日在科罗拉多州的雪人村。 这是有史以来第一次致力于此特定的会议 蛋白质的超家族。 这个超家族包括大量 进化保守和普遍表达的基因。 四跨果蛋白具有 与基本的生物学过程有关，例如细胞增殖， 粘附和运动，膜融合和肿瘤转移。 这是一个 作为这个家庭的第一批成员，相对较新的研究领域是 仅十年前就确定了。 对家庭的兴趣一直在增长 迅速在广泛的物种中发现了新成员 哺乳动物，线虫，果蝇和血吸虫。 而且，已知成员是 通过多种功能测定不断重新发现。 为了 例如，去年将一名家庭成员确定为推定 丙型肝炎病毒的受体。 由于四翼烷蛋白参与 多种蜂窝活动，该领域的研究人员来自不同 科学学科，包括免疫学，神经生物学，粘附，癌症 研究和病毒学。 迄今为止，该领域的通信已经 仅限于出版物，试剂交换和偶尔的联系 在个人科学家之间。 这次会议是首届四翼胺 研究会议，所有感兴趣的科学家都会亲自见面。 这 将对未来的合作研究非常有益 了解这种蛋白质超家族的作用机理。 会议的目的： 1。组装在这个迅速发展的领域工作的调查员以满足 彼此，介绍未发表的数据并讨论我们独特的问题 场地。 该会议旨在将高级科学家，一些会议召集在一起 长期参与，以及遇到的领域的新移民 无关研究领域的四翼烷蛋白。 一个重要的任务 会议是为初级科学家提供机会 未发表的研究通过抽象驱动的演示机制。 2。刺激各种各样的研究者之间的未来互动 学科 3。确定实验中未解决问题的实验方法。 4。解决命名法。 5。在更新的评论中总结该领域的当前知识为 发表在备受瞩目的科学杂志上。