PLACENTA--IMPLANTATION TO DELIVERY

胎盘——着床至分娩

• 批准号: 6225834
• 负责人: Richard Kermit Miller
• 金额: $ 1.2万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-22 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6225834
• 关键词: female; meeting /conference /symposium; placenta; pregnancy disorder; travel; trophoblast; women's health

DESCRIPTION (Adapted from applicant's description): The objective of the Conference, "The 14th Rochester Trophoblast Conference" is to provide a forum for the presentation and discussion of new molecular, biochemical, cellular, and clinical studies relevant to many aspects of human reproduction, including developmental, genetic, infectious disease, in particular HIV, toxicological and immunological aspects. The long range goal of this Conference is to foster interactions that could be expected to lead to improvements in human fertility and reduction in HIV infection in children, fetal wastage, reduction in the incidence of important gestational diseases such as premature rupture of membranes, fetal growth retardation, and pre-eclampsialpregnancy-induced hypertension. Additionally, interaction of scientists with those of the jointly held meeting of the Society for the Investigation of Early Pregnancy would be anticipated to lead to new insights into mechanisms of disease. Specific areas of focus are: 1) genetic regulation of blastocyst and placental development, 2) mechanisms of HIV infection and co-infection in utero 3) molecular regulation of essential hormones and growth factors/cytokines which foster pregnancy, 4) regulation of vascular supply and abnormalities of this in disease, 5) relation of inflammatory cells and pregnancy loss on survival, 6) growth factor networks in pregnancy loss, 7) composition and types of immune cells in reproductive tissues, 8) placental expression of major histocompatibility genes, 9) mechanisms of cellular defense against environmental toxicants, especially role of oxidant stress and 10) the effect of fetal health on adult outcomes. The format is designed to integrate recent findings in basic and clinical research. The meeting will be held from 4-8 October 2000. Major additional support is being sought from foundations and private corporations. The purpose of this application is to seek funding to support partial funding for 20 young investigators and trainees to both attend and present their research.

描述（改编自申请人的描述）：该项目的目标 会议，“第14届罗彻斯特滋养层会议”是提供一个论坛 用于介绍和讨论新的分子、生物化学、细胞、 以及与人类生殖许多方面相关的临床研究，包括 发育、遗传、传染病，特别是艾滋病毒、毒理学 和免疫学方面。本次会议的长远目标是促进 有望改善人类生育能力的相互作用 以及减少儿童艾滋病毒感染、胎儿浪费、减少 妊娠早期破裂等重要妊娠疾病的发生率 胎膜、胎儿生长迟缓和妊娠诱发的先兆子痫 高血压。此外，科学家与科学家之间的互动 早期妊娠研究学会联合召开会议 预计将带来对疾病机制的新见解。 具体重点领域是：1）囊胚和胎盘的遗传调控 发展，2）子宫内HIV感染和合并感染的机制 3) 必需激素和生长因子/细胞因子的分子调节 促进怀孕，4）调节血管供应和异常 这在疾病中，5）炎症细胞与流产的关系 生存，6) 妊娠丢失中的生长因子网络，7) 组成和 生殖组织中免疫细胞的类型，8) 胎盘表达 主要组织相容性基因，9) 细胞防御机制 环境毒物，特别是氧化应激的作用和10)的影响 胎儿健康对成人结局的影响。该格式旨在整合最新的 基础和临床研究的成果。会议将于4日至8日举行 2000 年 10 月。 正在寻求基金会和私人机构的主要额外支持 公司。 本申请的目的是寻求资金支持 为 20 名年轻研究者和实习生提供部分资助 展示他们的研究。