PRECLINICAL TOXICOLOGY & PHARMACOLOGY OF DRUGS DEVELOPED

临床前毒理学

• 批准号: 6352156
• 负责人: JOHN G PAGE
• 金额: --
• 依托单位: SOUTHERN RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-01-15 至 2003-01-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6352156
• 关键词: AIDS therapy; Primates; Rodentias; antiAIDS agent; antineoplastics; dogs; dosage; drug administration routes; drug screening /evaluation; mass spectrometry; neoplasm /cancer; neoplasm /cancer chemotherapy; neoplasm /cancer pharmacology; nonhuman therapy evaluation; nuclear magnetic resonance spectroscopy; pharmacokinetics; pharmacology; toxicology

The objective of this contract is to acquire pharmacologic and toxicologic data on new drugs for the treatment of Cancer and the Acquired Immunodeficiency Syndrome (AIDS) and AIDS-related illnesses. The data will be included in an Investigational New Drug (IND) application to the FDA which is required prior to the initiation of human clinical trials. Level A contract is 46,875 hours over 5 years. Level B contract is 93,750 hours over 5 years. This contract will be awarded at Level B because the laboratory has the capability, expertise and experience to do the amount of work required.

该合同的目的是获取药理学和 有关癌症和治疗新药的毒理学数据 获得的免疫缺陷综合征（AIDS）和与艾滋病相关的疾病。 数据将包括在调查新药（IND）中 申请在启动之前需要的FDA 人类临床试验。 A级合同在5年内为46,875小时。 B级合同是 5年内93,750小时。 该合同将在B级授予 因为实验室具有能力，专业知识和经验 完成所需的工作量。