CHANGES IN BODY COMPOSITION IN OBESE CHILDREN & ADOLESCENTS

肥胖儿童身体成分的变化

• 批准号: 6263436
• 负责人: REINALDO FIGUEROA-COLON
• 金额: $ 2.95万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-12-01 至 1999-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6263436
• 关键词: adolescence (12-20); body composition; caloric dietary content; child (0-11); clinical research; glucose metabolism; human subject; nutrition related tag; obesity; questionnaires; tomography; weight loss; adolescence (12-20); body composition; caloric dietary content; child (0-11); clinical research; glucose metabolism; human subject; nutrition related tag; obesity; questionnaires; tomography; weight loss

The main objective of this studyis to examine the changes in body composition for obese children and adolescents during a multidisciplinary weight loss program. In the United States obesity is one of the most prevalend and serious nutritional problems affecting children and adolescents. Strategies are needed to positively affect obese children and adolescents because there are significant complications in the areas of psychological development, orthopedic (bones and joints) injury, exercise tolerance, high blood pressure, elevated blood cholesterol and lipoproteins, and abnormal glucose metabolism. The main therapeutic goal in treating obese children and adolescents is the selective loss of total body fat mass without a detrimental change in total body fat-free mass or linear growth. Measurements of body composition are useful in assessing obesity and in monitoring the effects of intervention programs. To follow the changes in body composition (body fat, soft-lean tissue and bone) throughout the weight loss program, the obese children and adolescents will undergo anthropometric assessments, dual-energy X-ray absorptiometry, and abdominal computer tomography scan at baseline, 10 weeks and at 1-year. In addition, they will answer a series of psychosocial questionnaires, and daily calorie diaries and activity logs.

这项研究的主要目的是检查多学科减肥计划中肥胖儿童和青少年的身体成分变化。 在美国，肥胖是影响儿童和青少年的最流行和严重的营养问题之一。 需要策略来积极影响肥胖儿童和青少年，因为心理发育，骨科（骨骼和关节）损伤，运动耐受性，高血压，血压升高，血液胆固醇和脂蛋白以及异常葡萄糖代谢的领域存在重大并发症。 治疗肥胖儿童和青少年的主要治疗目标是总体脂肪质量的选择性损失，而无需对总体无脂肪质量或线性生长的不利变化。 人体组成的测量可用于评估肥胖和监测干预计划的影响。 为了遵循整个体重减轻计划中人体成分（体内脂肪，软液组织和骨骼）的变化，肥胖的儿童和青少年将接受人体测量评估，双能X射线吸收仪以及基线，10周，10周和1年的腹部计算机断层扫描。 此外，他们将回答一系列的社会心理问卷，每日卡路里日记和活动日志。