PSYCHOSOCIAL RISK FOR CARDIOVASCULAR DISEASE IN YOUTH

青少年心血管疾病的社会心理风险

• 批准号: 6272770
• 负责人: ADRIAN C ANGOLD
• 金额: $ 22.96万
• 依托单位: DUKE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6272770
• 关键词: African American; Native Americans; adolescence (12-20); aggression; angers; attitude; autonomic nervous system; behavioral /social science research tag; behavioral medicine; cardiovascular disorder; child (0-11); child rearing; clinical research; depression; disease /disorder proneness /risk; human puberty; human subject; isolation /deprivation; longitudinal human study; low socioeconomic status; socioenvironment

The aim of the Psychosocial Risk for Cardiovascular Disease in Youth Project (PRCVDYP) is to use three ongoing general population studies of youth as basis for examining the development of psychosocial risk for CVD. In relation to the Program Project as a whole, the PRCVDYP will address and expand upon Programmatic Objective 2 in examining the questions of whether and how harsh environments in childhood and adolescence (e.g., poverty and negative parenting styles) lead to negative psychosocial risk profiles (hostility, depression, and social isolation), and in turn whether and how such psychosocial risks translate into more proximal risks for CVD (heart rate and blood pressure indicaes, adiposity, smoking and alcohol use). We will use (a) ethnically diverse, (b) representative general population samples aged 9 - 16 and their parents to study (c) cross-generational predicators of (d) multiple components of (e) hostility, (f) depression and (g) social isolation, (h) over repeated waves of measurement. We will pay particular attention to the possibility that (1) different patterns of risk evolve in males and females at (j) puberty. The PRCVDYP builds on three current, NIH-funded studies: The Great Smoky Mountains Study (GSMS), a longitudinal study of risk for psychiatric disorder in a representative population-based sample of 1,072 youth in western North Carolina; The American Indian Study (AIS), which uses the same design and methods to study 354 American Indian (Cherokee) youth from the same geographic area as the GSMS; and Caring for Children in the Community Study (CCCS), a similar study of 1,200 youth set in an area of eastern North Carolina where 50 percent of the population are African American. In each sample, approximately 50 percent are female. Socio-economic status, social adversity, social isolation, depression, weight, height, pubertal status (morphological and hormonal), family functioning, and harsh parenting style are measured in these studies over three waves of data collection. Funds are requested to add to the ongoing studies in the following ways: 1. to analyze the audiotapes of the GSMS, AIS and CCCS interviews of parents and children, using the interpersonal Hostility Assessment Technique (IHAT), which uses vocal stylistics to assess underlying hostility; 2. to administer the Cook-Medley Hostility Scale to assess cynical, angry and aggressive attitudes in 800 parents and youth from the CCCS; 3. to assess SNS and PNS tone and reactivity to physical (assuming upright posture) and mental (attentional task) challenges to 800 youth from the CCCS; and 4. to repeat all three additional studies in two follow-up waves of 180 youth from the CCCS sample, selected for being at high and low CVD risk. We hypothesize that (1) low SES youth will wxhibit, in addition to increased levels of the psychosocial and behavioral risk factors under study, increased SNS tone and reactivity to mental challenge, as well as decreased INS tone; (2) Depression, social isolation, and harsh parenting will interact with low SES to increase CVD risk.

青年人心血管疾病的社会心理风险的目的 项目（PRCVDYP）是使用三项正在进行的一般人群研究 青年作为研究社会心理风险发展的基础 对于CVD。 关于整个程序项目，PRCVDYP 将解决并扩展编程目标2 关于童年和如何恶劣环境的问题 青春期（例如，贫困和否定育儿方式）导致 负面的社会心理风险概况（敌对，抑郁和社会 隔离），反过来又是这种社会心理的风险 转化为CVD的近端风险（心率和血液 压力指示，肥胖，吸烟和饮酒）。 我们将使用 （a）种族多样的，（b）代表性的一般人群样本 9-16岁，他们的父母学习（c）跨代 （d）（e）敌意的多个组成部分，（f）抑郁症的谓词 （g）社会隔离，（h）重复测量波。 我们 将特别注意（1）不同的可能性 （J）青春期的男性和女性的风险模式。 PRCVDYP建立在三项最新的，NIH资助的研究之上：伟大 烟熏山研究（GSM），一项纵向研究 基于人群的代表性样本的精神疾病 北卡罗来纳州西部的1,072名青年；美洲印第安人研究（AIS）， 使用相同的设计和方法来研究354美洲印第安人 （切诺基）与GSM相同地理区域的青年；和关怀 对于社区研究（CCC）的儿童，1,200的类似研究 年轻人位于北卡罗来纳州东部的地区50％ 人口是非裔美国人。 在每个样本中，约有50个 百分比是女性。 社会经济地位，社会逆境，社会 隔离，抑郁，体重，身高，青春期状态（形态学 和荷尔蒙），家庭功能和苛刻的育儿风格是 在这些研究中测量了三个数据收集波。 要求资金添加到正在进行的研究中 方式：1。分析GSM，AIS和CCCS访谈的录音带 父母和孩子，使用人际敌意评估 技术（IHAT），它使用声音文体来评估基础 敌意; 2。管理库克 - 梅德利敌对量表以评估 来自800名父母和青年的愤世嫉俗，愤怒和积极的态度 CCCS； 3。评估SNS和PNS音调以及对物理的反应性 （假设直立的姿势）和心理（注意力）挑战 来自CCC的800名青年；和4。重复所有其他三项研究 在CCC样本中的180名青年的两次后续浪中，被选为 CVD风险高和低。 我们假设（1）低SES青年还将 下降的社会心理和行为风险因素水平增加 研究，增加了SNS语调和对心理挑战的反应性 随着INS音调的降低； （2）抑郁，社会孤立和苛刻 育儿将与低SES相互作用，以增加CVD风险。