An inter-disciplinary approach to understanding and intervening on contextual factors that shape HIV-risk for young women and men in South Africa

采用跨学科方法来理解和干预影响南非年轻女性和男性艾滋病毒风险的背景因素

• 批准号: MR/T029803/1
• 负责人: Rachel Jewkes
• 金额: $ 223.01万
• 依托单位: South African Medical Research Council
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2020
• 资助国家: 英国
• 起止时间: 2020 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=MR%2FT029803%2F1
• 关键词: inter; disciplinary; approach; understanding; intervening

Globally, and in South Africa in particular, HIV remains a major public health challenge. In KwaZulu-Natal Province, the functional epicentre of the global HIV-epidemic, young women and girls (18-24) are particularly at risk of acquiring HIV, and young men, are the only group in the country with an rising HIV-incidence. These high rates of HIV-acquisition are driven by harsh social contexts of poverty, inequitable gender norms, and widespread levels of violence, driven by the long legacy of apartheid. This project seems to achieve three aims: 1) to understand how social contexts shape young people's HIV-acquisition risk; 2) to develop an intervention to support young women and men to take control of their lives and HIV-acquisition risk; and 3) assess the feasibility, acceptability and potential impact of this intervention.To achieve aim 1 we will use unique existing quantitative data sets to understand how social contexts shape HIV-acquisition risk in young people and then undertake long-term participatory research with 16 youth peer research associates (YPRAs) hired from two sites in KwaZulu-Natal - urban informal settlements and rural KwaZulu-Natal. Through this we will understand in multiple ways how risk manifests itself. To achieve aim 2 we will work with the YPRAs and the team of researchers to develop an intervention with resonates with young women's and men's live. To achieve aim 3 we will undertake a pilot evaluation of the intervention, assessing quantitative and qualitatively whether the intervention was felt to be feasible and acceptable by young people, and whether it shows any evidence of effect.We will share results with the community through producing plain language summaries of the research we produce, and also a short video at endline, all in collaboration with the YPRAs.

在全球范围内，特别是在南非，艾滋病毒仍然是一项重大的公共卫生挑战。在夸祖鲁-纳塔尔省，全球艾滋病毒流行的功能中心，年轻妇女和女孩（18-24岁）尤其面临感染艾滋病毒的风险，而年轻男性是该国唯一艾滋病毒发病率上升的群体。如此高的艾滋病毒感染率是由贫困、不平等的性别规范和普遍存在的暴力等严酷的社会环境造成的，而这些都是由种族隔离的长期遗留问题造成的。该项目似乎实现了三个目标：1）了解社会环境如何影响年轻人感染艾滋病毒的风险； 2) 制定干预措施，支持青年男女掌控自己的生活和艾滋病毒感染风险； 3) 评估该干预措施的可行性、可接受性和潜在影响。为了实现目标 1，我们将使用独特的现有定量数据集来了解社会背景如何影响年轻人感染艾滋病毒的风险，然后与 16 名儿童进行长期参与性研究从夸祖鲁-纳塔尔省的两个地点聘用的青年同伴研究助理（YPRA）——城市非正式住区和夸祖鲁-纳塔尔省农村地区。通过这一点，我们将以多种方式了解风险是如何表现出来的。为了实现目标 2，我们将与 YPRAs 和研究团队合作，制定一项与年轻女性和男性生活产生共鸣的干预措施。为了实现目标 3，我们将对干预措施进行试点评估，定量和定性评估干预措施是否被年轻人认为可行和可接受，以及是否显示出任何效果证据。我们将通过制作与社区分享结果我们制作的研究的简单语言摘要，以及结尾处的短视频，所有这些都是与 YPRAs 合作的。

项目成果

Beyond HIV prevalence: identifying people living with HIV within underserved areas in South Africa.

• DOI: 10.1136/bmjgh-2020-004089
• 发表时间: 2021-04
• 期刊: BMJ global health
• 影响因子: 8.1
• 作者: Kim H;Tanser F;Tomita A;Vandormael A;Cuadros DF
• 通讯作者: Cuadros DF

Intimate Partner Violence and the HIV Care and Treatment Cascade Among Adolescent Girls and Young Women in DREAMS, South Africa.

• DOI: 10.1097/qai.0000000000002843
• 发表时间: 2022-02-01
• 期刊: Journal of acquired immune deficiency syndromes (1999)
• 作者: Gibbs A;Reddy T;Closson K;Cawood C;Khanyile D;Hatcher A
• 通讯作者: Hatcher A

A Prospective Analysis of the Interrelationship between Physical Intimate Partner Violence and Alcohol Use: A Post-Hoc Analysis of Young Women Involved in the Stepping Stones and Creating Futures Trial in South Africa

• DOI: 10.1177/08862605221084738
• 发表时间: 2022-04-09
• 期刊: JOURNAL OF INTERPERSONAL VIOLENCE
• 影响因子: 2.5
• 作者: Gibbs, Andrew;Chirwa, Esnat;Dunkle, Kristin
• 通讯作者: Dunkle, Kristin

Investigating the impact of HIV on patients with first episode psychosis: a study protocol for a longitudinal cohort study.

• DOI: 10.1136/bmjopen-2020-046593
• 发表时间: 2021-05-21
• 期刊: BMJ open
• 影响因子: 2.9
• 作者: Chhagan U;Ntlantsana V;Tomita A;Naidu T;Chiliza B;Paruk S
• 通讯作者: Paruk S

High-Risk Contexts for Violence Against Women: Using Latent Class Analysis to Understand Structural and Contextual Drivers of Intimate Partner Violence at the National Level.

• DOI: 10.1177/08862605221086642
• 发表时间: 2023-01
• 期刊: JOURNAL OF INTERPERSONAL VIOLENCE
• 影响因子: 2.5
• 作者: Brown, Laura J.;Lowe, Hattie;Gibbs, Andrew;Smith, Colette;Mannell, Jenevieve
• 通讯作者: Mannell, Jenevieve