HOME CARE MONITORING OF HIV EXPOSED CHILDREN

对感染艾滋病毒的儿童进行家庭护理监测

• 批准号: 2891215
• 负责人: MARY Woods BYRNE
• 金额: $ 8.72万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2891215
• 关键词: adult human (21+); child care; child physical development; clinical research; health surveys; home health care; human subject; immunity; infant human (0-1 year); longitudinal human study; mathematical model; model design /development; nursing care evaluation; nutrition; nutrition related tag; pediatric AIDS; public health nursing

The overall objective of this proposal is to refine and evaluate the proposed growth-immune support-nutrition-interaction (GINI) model as an approach to clinical description and monitoring of HIV exposed infants in home care programs. The specific research aims of this proposal are: (1) to evaluate, select, pilot test, and possibly modify existing data collection instruments which measure the growth and the interaction dimensions of infants cared for at home; (2) to describe the influence of the four factors in the model (growth, immune support, nutrition, and interaction) on each other and on the longitudinal progression of HIV disease and perinatally exposed infants in a home care program; and (3) to evaluate the GINI theoretical model as a guide for public health nursing visits during the first year of life in a cohort of infants exposed perinatally to HIV infection. Methodological studies are undertaken to establish reliability, validity, and feasibility of instruments for measuring child weight and length, and for caregiver-child interactions. The results of the these studies will be used to select instrumentation for a longitudinal involved prospective monitoring of HIV-exposed children in establishing Home Care programs. Patterns will be identify for the GINI variables during the first year of life and compared to children who are truly infected, seroreverters, and a comparison group of infants without perinatal HIV exposure. Nurses who use the model as the basis for assessment of HIV-exposed infants in the home will rate its utility. Training in design and advanced statistics that is accomplished in the first months of the award will be applied to the implementation and analysis of the prospective study in the subsequent months and years. The work will serve as a basis for future study of interventions appropriate to home care settings that will improve the quality of life and delay the impact of disease in HIV exposed and HIV infected infants and children living at home.

该提议的总体目的是完善和评估 拟议的生长免疫支撑 - - 养育相互作用（GINI）模型作为一种 临床描述和监测HIV暴露婴儿的方法 家庭护理计划。该提案的具体研究目的是：（1） 评估，选择，试点测试，并可能修改现有数据 衡量增长和相互作用的收集工具 在家照顾的婴儿的尺寸； （2）描述 模型中的四个因素（增长，免疫支持，营养和 相互作用）彼此和HIV的纵向进展 家庭护理计划中的疾病和围产期暴露的婴儿； （3）到 评估Gini理论模型作为公共卫生护理指南 在一年的一年中，一群婴儿的访问 围绕HIV感染。进行方法论研究 建立工具的可靠性，有效性和可行性 测量儿童体重和长度，以及照顾者与孩子的互动。 这些研究的结果将用于选择仪器 纵向涉及对艾滋病毒暴露的前瞻性监测 建立家庭护理计划的孩子。模式将被识别 Gini变量在生命的第一年，并与儿童相比 真正受感染的，无声的人和一个婴儿的比较组 没有围产期HIV暴露。使用该模型作为基础的护士 评估房屋中受艾滋病毒暴露的婴儿的评估将评估其效用。 在设计和高级统计的培训中 裁决的头几个月将应用于实施和 在随后的几个月和几年中对前瞻性研究的分析。这 工作将作为对干预措施的未来研究的基础 到家庭护理环境，将改善生活质量并延迟 疾病在艾滋病毒暴露和艾滋病毒感染的婴儿和儿童中的影响 住在家里。